An ionizable lipid toolbox for RNA delivery.
An ionizable lipid toolbox for RNA delivery.
复制标题
DOI:
10.1038/s41467-021-27493-0
复制
发表时间:
2021-12-13
影响因子:
16.6
通讯作者:
Mitchell MJ
中科院分区:
文献类型:
--
作者:
Han X;Zhang H;Butowska K;Swingle KL;Alameh MG;Weissman D;Mitchell MJ
Recent years have witnessed incredible growth in RNA therapeutics, which has benefited significantly from decades of research on lipid nanoparticles, specifically its key component—the ionizable lipid. This comment discusses the major ionizable lipid types, and provides perspectives for future development. RNA therapeutics have benefited significantly from decades of research on lipid nanoparticles, specifically its key component—the ionizable lipid. This comment discusses the major ionizable lipid types, and provides perspectives for future development.
登录
查看更多内容
影响因子:
7.8
作者:
Buschmann MD;Carrasco MJ;Alishetty S;Paige M;Alameh MG;Weissman D
通讯作者:
Weissman D
影响因子:
10.8
作者:
Kauffman, Kevin J.;Dorkin, J. Robert;Anderson, Daniel G.
通讯作者:
Anderson, Daniel G.
影响因子:
2.8
作者:
Knapp, Christopher M.;Guo, Penghong;Whitehead, Kathryn A.
通讯作者:
Whitehead, Kathryn A.
影响因子:
16.6
作者:
Jayaraman, Muthusamy;Ansell, Steven M.;Mui, Barbara L.;Tam, Ying K.;Chen, Jianxin;Du, Xinyao;Butler, David;Eltepu, Laxman;Matsuda, Shigeo;Narayanannair, Jayaprakash K.;Rajeev, Kallanthottathil G.;Hafez, Ismail M.;Akinc, Akin;Maier, Martin A.;Tracy, Mark A.;Cullis, Pieter R.;Madden, Thomas D.;Manoharan, Muthiah;Hope, Michael J.
通讯作者:
Hope, Michael J.
DOI:
10.1056/nejmoa2035389
发表时间:
2021-02-04
期刊:
The New England journal of medicine
影响因子:
--
作者:
Baden LR;El Sahly HM;Essink B;Kotloff K;Frey S;Novak R;Diemert D;Spector SA;Rouphael N;Creech CB;McGettigan J;Khetan S;Segall N;Solis J;Brosz A;Fierro C;Schwartz H;Neuzil K;Corey L;Gilbert P;Janes H;Follmann D;Marovich M;Mascola J;Polakowski L;Ledgerwood J;Graham BS;Bennett H;Pajon R;Knightly C;Leav B;Deng W;Zhou H;Han S;Ivarsson M;Miller J;Zaks T;COVE Study Group
通讯作者:
COVE Study Group