The hydrogen peroxide induced enhancement of DNA cleavage in the ambient light photolysis of CpFe(CO)2Ph: a potential strategy for targeting cancer cells.
The hydrogen peroxide induced enhancement of DNA cleavage in the ambient light photolysis of CpFe(CO)2Ph: a potential strategy for targeting cancer cells.
复制标题
过氧化氢在 CpFe(CO)2Ph 的环境光光解中诱导 DNA 裂解增强：靶向癌细胞的潜在策略。
DOI：
10.1016/j.bmcl.2005.06.102
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发表时间：
2005
影响因子：
2.7
通讯作者：
Thomas A. Shell
中科院分区：
文献类型：
--
作者：
D. L. Mohler;Thomas A. Shell
DNA strand scission is produced by the ambient light photolysis of CpFe(CO)2Ph and H2O2, a result that shows potential as a means of targeting tumors, due to the high levels of hydrogen peroxide in cancer cells. This cleavage process is dependent on the concentration of both CpFe(CO)2Ph and H2O2, and preliminary experiments implicate both carbon-centered radicals and reactive oxygen species.
影响因子：
11.2
作者：
T. Szatrowski;C. Nathan
通讯作者：
T. Szatrowski;C. Nathan