Prevention of duodenal ulcer recurrence.
Prevention of duodenal ulcer recurrence.
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预防十二指肠溃疡复发。
DOI：
10.7326/0003-4819-105-5-757
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发表时间：
1986
影响因子：
39.2
通讯作者：
W. Strum
中科院分区：
文献类型：
--
作者：
W. Strum
用西咪替丁400mg或雷尼替丁150mg，每晚1次，或用硫糖铝1g，每天2次治疗复发性十二指肠溃疡，可在大约75%的患者中预防长达1年。由于这些药物通常具有相同的疗效，因此要根据患者以前的用药经验和耐受性、潜在的副作用、药物相互作用的风险、给药频率和成本进行选择。这些药物不会改变十二指肠溃疡的自然病史，如果没有长期副作用，治疗可能需要持续1年以上。应该做出额外的努力来帮助吸烟者戒烟。维持治疗期间复发性十二指肠溃疡的患者可采用全剂量治疗。如果最佳药物治疗不能有效预防复发或并发症，则需要手术治疗。
Recurrent duodenal ulcers, treated with cimetidine, 400 mg, or ranitidine, 150 mg, once nightly, or with sucralfate, 1 g twice daily, can be prevented in approximately 75% of patients for up to 1 year. Because these drugs are generally of equal efficacy, the choice is based on the patient's previous drug experience and tolerance, potential side effects, risk of drug interaction, frequency of administration, and cost. These medications do not alter the natural history of duodenal ulcer disease, and therapy may need to continue for longer than 1 year if there are no long-term side effects. Extra efforts should be made to help cigarette smokers discontinue smoking. Patients who have recurrent duodenal ulcers during maintenance therapy can be retreated with full-dose therapy. If optimal drug therapy is unsuccessful in preventing frequent recurrences or complications, surgical treatment is indicated.
常用饮料对人类胃酸分泌的相对刺激作用。
影响因子：
29.4
作者：
McArthur,K;Hogan,D;Isenberg,JI
通讯作者：
Isenberg,JI
采用剖腹探查术、近端胃迷走神经切断术和 H2 受体拮抗剂治疗 Zollinger-Ellison 综合征。
影响因子：
29.4
作者：
Richardson,CT;Peters,MN;Feldman,M;McClelland,RN;Walsh,JH;Cooper,KA;Willeford,G;Dickerman,RM;Fordtran,JS
通讯作者：
Fordtran,JS