Quantitative proteome analysis: Methods and applications
Quantitative proteome analysis: Methods and applications
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DOI:
10.1086/374756
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发表时间:
2003-06-15
影响因子:
6.4
通讯作者:
Aebersold, R
中科院分区:
文献类型:
--
作者:
Aebersold, R
With the completion of the genomic sequencing of a number of species, including that of humans, much attention is currently focused on how the information in these sequences might be interpreted in terms of the structure, function, and control of biologic systems and processes. Quantitative proteome analysis, the global analysis of protein expression, is increasingly being used as a method to study steady-state and perturbation-induced changes in protein profiles. The rationale for quantitative proteome analysis is described, along with a new technology for high throughput quantitative profiling of proteins in complex mixtures and its current status with selected applications.