BACTERIAL ENDOPHTHALMITIS FOLLOWING SUTURE REMOVAL AFTER PENETRATING KERATOPLASTY

BACTERIAL ENDOPHTHALMITIS FOLLOWING SUTURE REMOVAL AFTER PENETRATING KERATOPLASTY
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DOI:
10.1016/0002-9394(75)90217-2
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发表时间:
1975-01-01
影响因子:
4.2
通讯作者:
BINDER, PS
BINDER, PS
中科院分区:
医学1区
文献类型:
--
作者:
FORSTOT, SL;ABEL, R;BINDER, PS

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在穿透性角膜移植术后拆除角膜缝线后发生的3例细菌性眼内炎中,2例与伤口裂开相关,1例与伤口裂开无关。可能导致伤口裂开和后续感染的因素包括:使用精细缝合材料、皮质类固醇和慢性局部抗生素;早期拆除角膜缝线;拆除缝线前后缺乏严格的无菌操作;以及可能因玻璃体嵌顿而保持开放的缝合道。在拆线后3天内,可能发生晚期角膜伤口裂开,随后发生眼内炎。在拆线前后使用局部抗生素可降低感染的可能性。此外,患者和外科医生早期识别眼内感染,立即进行抗菌和抗炎治疗,可以保护有用的视力。
Of three cases of bacterial endophthalmitis occurring after removal of corneal sutures following penetrating keratoplasty, two were associated with wound dehiscence and one was not. Factors that may predispose to wound dehiscence and subsequent infection are: use of fine suture material, corticosteroids, and chronic topical antibiotics; early removal of corneal sutures; lack of adherence to strict asepsis prior to and after suture removal; and open suture tracts that may be kept open by incarceration of vitreous strands. Late corneal wound dehiscence may occur with subsequent development of endophthalmitis as long as three days after suture removal. The use of topical antibiotics before and after suture removal may decrease the potential for infection. In addition, early recognition of intraocular infection by the patient and the surgeon for immediate institution of antimicrobial and anti-inflammatory therapy may preserve useful vision.