Distortion products otoacoustic emissions in diagnosis of hearing loss in Down syndrome
Distortion products otoacoustic emissions in diagnosis of hearing loss in Down syndrome
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DOI：
10.1016/s0165-5876(98)00106-2
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发表时间：
1998-10-15
影响因子：
1.5
通讯作者：
Musiatowicz, M
中科院分区：
文献类型：
--
作者：
Hassmann, E;Skotnicka, B;Musiatowicz, M
本研究旨在探讨唐氏综合症患者的听力损害特征。47名患有唐氏综合症的儿童和14名成人参与了这项研究。在所有病例中，进行完整的耳鼻喉检查，然后进行听力学评估。根据年龄、智力水平和中耳状态进行以下检查：纯音“播放听力测定”、鼓室测量、声反射、听觉脑反应（ABR）和失真产物耳声发射（DPOAE）。将结果与年龄匹配的对照组进行比较。在唐氏综合征患儿中，我们经常发现中耳传导功能受损，这是病理鼓室测量法所表达的。56%的耳检出B型和C型鼓室。唐氏综合征患儿DPOAE的振幅低于对照组。这种差异在患有唐氏综合症的成年人中表现得更为明显。无传导性听力损失的唐氏综合征患者的DPOAE检查结果提示与早期内耳损伤相关。(C) 1998爱思唯尔科学爱尔兰有限公司版权所有。
This study was carried out to investigate the features of hearing impairment in subjects with Down syndrome. Forty-seven children and 14 adults with Down syndrome were included in the study. In all cases, a complete otorhinolaryngological examination was performed, followed by audiological assessment. Depending on age, intellectual level and middle ear status the following examinations were performed: pure-tone 'play audiometry', tympanometry, acoustic reflex, auditory brain response (ABR) and distortion products otoacoustic emissions (DPOAE). The results were compared with age matched control groups. Among the group of children with Down syndrome, we have frequently found impairment of the conductive function of the middle ear which was expressed by pathological tympanometry. Tympanometry of B and C type was detected in 56% of ears. The amplitude of DPOAE was lower in children with Down syndrome than in the control group. This difference was more expressed in adults with Down syndrome. DPOAE examination results in subjects with Down syndrome without conductive hearing loss indicate early age related inner ear impairment. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.