Cohort Profile: The INMA-INfancia y Medio Ambiente-(Environment and Childhood) Project

Cohort Profile: The INMA-INfancia y Medio Ambiente-(Environment and Childhood) Project
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DOI:
10.1093/ije/dyr054
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发表时间:
2012-08-01
影响因子:
7.7
通讯作者:
Sunyer, Jordi
Sunyer, Jordi
中科院分区:
医学1区
文献类型:
--
作者:
Guxens, Monica;Ballester, Ferran;Sunyer, Jordi

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儿童从受孕到青春期结束的身体、社会和智力发展需要一个既保护又保护其健康的环境。越来越多的儿童疾病与不安全的环境有关。产前和生命早期暴露与儿童发育和健康有关,并易受成年后期影响。INMA-INfancia y Medio Ambiente(环境与儿童)项目是西班牙出生队列网络,旨在研究怀孕期间和幼儿期空气、水和饮食中的环境污染物对儿童生长发育的作用。INMA基于三个出生队列获得的经验:Ribera d 'Ebre队列(2002年),该队列评估了一个地区的神经发育情况,该地区的有机氯化合物(OCs)和源自氯碱工厂排放的汞含量很高;Menorca队列研究了生命早期接触空气传播的刺激物和过敏原与过敏和哮喘的关系;格拉纳达队列(668年),研究出生时婴儿生殖健康疾病的发生率
The physical, social and intellectual development of children from conception to the end of adolescence requires an environment that is both protected and protective of their health. A growing number of diseases in children are linked to unsafe environments. Pre-natal and early life exposures are associated with child development and health and predispose to late adult effects.The INMA—INfancia y Medio Ambiente—(Environment and Childhood) Project is a network of birth cohorts in Spain that aim to study the role of environmental pollutants in air, water and diet during pregnancy and early childhood in relation to child growth and development. INMA was based on the experiences acquired by three birth cohorts: the cohort of Ribera d’Ebre (n ¼ 102), which assessed neurological development in an area with high levels of organochlorine compounds (OCs) and mercury originating from the emission of a chloralkali plant; the cohort of Menorca (n ¼ 530), which studied associations of early life exposure to air-borne irritants and allergens on allergy and asthma; and the cohort of Granada (n ¼ 668), which studied the incidence of infant reproductive health disorders at birth