Solubility of three types of benzamide derivatives in toluene, ethyl acetate, acetone, chloroform, methanol, and water at temperatures ranging from 288.15 to 328.15 K at atmospheric pressure
Solubility of three types of benzamide derivatives in toluene, ethyl acetate, acetone, chloroform, methanol, and water at temperatures ranging from 288.15 to 328.15 K at atmospheric pressure
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常压、288.15~328.15 K温度下三种苯甲酰胺衍生物在甲苯、乙酸乙酯、丙酮、氯仿、甲醇和水中的溶解度
DOI：
10.1016/j.molliq.2015.01.045
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发表时间：
2015-04-01
影响因子：
6
通讯作者：
Yang, Guangde
中科院分区：
文献类型：
--
作者：
Chen, Jiangang;Nan, Guanjun;Yang, Guangde
采用常压紫外分光光度法测定了 3 种苯甲酰胺衍生物 S-1、S-2 和 S-3 在 6 种不同极性的纯溶剂（包括甲苯、乙酸乙酯、丙酮、氯仿、甲醇和水）中在 288.15 至 328.15 K（丙酮为 318.15 K）温度范围内的溶解度。 S-1、S-2和S-3在所选溶剂中的溶解度随着温度的升高而增加。发现S-1在甲醇中的摩尔分数溶解度最高（1.2464 x 103，328.15 K），并且S-1在所选溶剂中的溶解度顺序如下：甲醇>丙酮>氯仿>乙酸乙酯>甲苯>水。 Sy 在氯仿中的摩尔分数溶解度最高（7.6750 x 103，328.15 K），Sy 在六种溶剂中的溶解度顺序为：氯仿>甲醇>丙酮>乙酸乙酯>甲苯>水。然而，对于 S-3，发现丙酮中的摩尔分数溶解度最高（318.15 K 时为 1.1520 x 103），顺序为丙酮 > 甲醇 > 乙酸乙酯 > 氯仿 > 甲苯 > 水。实验溶解度数据与修正的Apelblat方程、lambda h模型和理想模型相关。三个模型计算的溶解度与实验值吻合良好，修正的 Apelblat 方程提供了最好的相关结果。根据溶解度数据，利用van't Hoff方程计算S-1、S-2和S-3的溶解焓和熵。 (C) 2015 Elsevier B.V. 保留所有权利。
The solubility of three types of benzamide derivatives S-1, S-2, and S-3 in six pure solvents, with various polarities, including toluene, ethyl acetate, acetone, chloroform, methanol, and water at temperatures ranging from 288.15 to 328.15 K (318.15 K for acetone) was determined by ultraviolet spectrophotometry at atmospheric pressure. The solubility of S-1, S-2, and S-3 in the selected solvents increased with the increase in temperature. The mole fraction solubility of S-1 was found to be the highest in methanol (1.2464 x 103 at 328.15 K) and the solubility of S-1 in the selected solvents was in the following order: methanol > acetone > chloroform > ethyl acetate > toluene > water. The highest mole fraction solubility of Sy was found in chloroform (7.6750 x 103 at 328.15 K) and the solubility of Sy in the six solvents followed the order: chloroform> methanol > acetone > ethyl acetate >toluene > water. However, for S-3 the mole fraction solubility was found to be highest in acetone (1.1520 x 103 at 318.15 K) and the order was acetone > methanol > ethyl acetate > chloroform > toluene > water. The experimental solubility data were correlated with the modified Apelblat equation, lambda h model, and ideal model. The calculated solubility by the three models showed good agreement with the experimental values and the modified Apelblat equation provided the best correlation results. Based on the solubility data, the dissolution enthalpy and entropy of S-1, S-2, and S-3 were calculated by using the van't Hoff equation. (C) 2015 Elsevier B.V. All rights reserved.