A randomized controlled clinical treatment trial for World Trade Center attack-related PTSD in disaster workers
A randomized controlled clinical treatment trial for World Trade Center attack-related PTSD in disaster workers
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DOI：
10.1097/nmd.0b013e3181568612
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发表时间：
2007-10-01
影响因子：
1.9
通讯作者：
Marmar, Charles
中科院分区：
文献类型：
--
作者：
Difede, JoAnn;Malta, Loretta S.;Marmar, Charles
本文介绍了一项针对救灾人员的认知行为治疗 (CBT) 的对照临床试验。尽管全世界救灾人员的创伤后应激障碍（PTSD）发病率很高，但目前还没有针对创伤后应激障碍（PTSD）治疗的随机试验。参与者被随机分配接受为期 12 周的认知行为暴露治疗（CBT，N = 15）或照常治疗（N = 16）。 8 名 CBT 和 14 名照常治疗参与者完成了治疗。一项检查临床医生管理的 PTSD 量表评分变化的方差分析发现，时间、组和时间 X 组交互作用的显着主效应 (p < 0.010)，CBT 组的症状评分下降幅度显着更大。组间效应很大。辍学与较低的收入、较少的教育和较高的饮酒量有关。该项目展示了灾难性事件后招募的可行性、由 CBT 和暴露组成的简短重点干预措施的相关性，以及消除与收入和教育相关的治疗保留障碍的必要性。
This article describes a controlled clinical trial of cognitive-behavioral treatment (CBT) for disaster workers. Despite high rates of PTSD in disaster workers worldwide, there have been no randomized trials of PTSD treatment. Participants were randomly assigned to a 12-week cognitive-behavioral exposure treatment (CBT, N = 15) or a treatment-as-usual (N = 16) condition. Eight CBT and 14 treatment-as-usual participants completed treatment. An ANOVA examining changes in Clinician-Administered PTSD Scale scores found significant main effects of Time, Group, and a Time X Group interaction (p's < 0.010) with a significantly greater decline in symptom scores in the CBT group. Between-group effect sizes were large. Dropout was associated with lower income, less education, and higher alcohol consumption. This project demonstrates the feasibility of recruitment in the aftermath of a catastrophic event, the relevance of a brief focused intervention comprised of CBT and exposure, and the need to eliminate barriers to treatment retention associated with income and education.