Trends in preterm birth: singleton and multiple pregnancies in the Netherlands, 2000-2007
Trends in preterm birth: singleton and multiple pregnancies in the Netherlands, 2000-2007
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DOI：
10.1111/j.1471-0528.2011.03010.x
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发表时间：
2011-09-01
影响因子：
5.8
通讯作者：
Ravelli, A. C. J.
中科院分区：
文献类型：
--
作者：
Schaaf, J. M.;Mol, B. W. J.;Ravelli, A. C. J.
几项研究报告称，发达国家的早产趋势呈上升趋势，主要原因是医学上指征性早产的增加。我们的目的是描述荷兰单胎和多胎妊娠中早产的趋势。设计前瞻性队列研究。全国性研究。从2000年到2007年，我们研究了1451 246名孕妇。方法评估早产趋势。我们将早产细分为产前胎膜过早破裂（pPROM）后的自发性早产、医学指示性早产和无pPROM的自发性早产。我们分别对单例和多例进行了分析。主要结局指标主要结局为早产，定义为妊娠37周前出生，极早产(
Objective Several studies have reported increasing trends in preterm birth in developed countries, mainly attributable to an increase in medically indicated preterm births. Our aim was to describe trends in preterm birth among singleton and multiple pregnancies in the Netherlands.Design Prospective cohort study.Setting Nationwide study.Population We studied 1 451 246 pregnant women from 2000 to 2007.Methods We assessed trends in preterm birth. We subdivided preterm birth into spontaneous preterm birth after premature prelabour rupture of membranes (pPROM), medically indicated preterm birth and spontaneous preterm birth without pPROM. We performed analyses separately for singletons and multiples.Main outcome measures The primary outcome was preterm birth, defined as birth before 37 weeks of gestation, with very preterm birth (