Micro-reaction chamber electrodes for neural stimulation and recording.
Micro-reaction chamber electrodes for neural stimulation and recording.
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用于神经刺激和记录的微反应室电极。
DOI：
10.1109/iembs.2011.6090146
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Gluckman,BruceJ
中科院分区：
文献类型：
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作者：
Shanmugasundaram,Balaji;Gluckman,BruceJ
优选具有较小几何面积的生物相容性电极，以提高神经记录和刺激应用的选择性。我们引入了微反应室（μRC）的概念，其中电极背板内的体积用于限制和隔离用于电荷通道的电化学反应。 URC 电极设计有助于降低阻抗并提高电荷存储容量，而无需改变活性位点的几何形状。在这里，我们证明，与其他设计相比，由 50 μm 直径的微丝制成的 μRC 电极在磷酸盐缓冲盐水溶液中显着提高了电荷存储容量并降低了生理相关频率下的阻抗。
Biocompatible electrodes with smaller geometric area are preferred to improve the selectivity of the neural recording and stimulation applications. We introduce the concept of a micro-reaction chamber (μRC) in which a volume within the electrode back plane is used to confine and sequester the electrochemical reactions used for charge passage. The URC electrode design helps decrease impedance and improves the charge storage capacity without altering the geometry of the active site. Here we demonstrate that μRC electrodes fabricated from 50 μm diameter microwire have significantly improved charge storage capacity and lowered impedance at physiologically relevant frequencies in phosphate buffered saline solution compared with other designs.