High prevalence of unintended pregnancies in HIV-positive women of reproductive age in Ontario, Canada: a retrospective study
High prevalence of unintended pregnancies in HIV-positive women of reproductive age in Ontario, Canada: a retrospective study
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DOI：
10.1111/j.1468-1293.2011.00946.x
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发表时间：
2012-02-01
期刊：
影响因子：
3
通讯作者：
Walmsley, S. L.
中科院分区：
文献类型：
--
作者：
Loutfy, M. R.;Raboud, J. M.;Walmsley, S. L.
有推测，但很少有数据，在艾滋病毒阳性妇女的意外怀孕率高。我们调查了艾滋病毒阳性的育龄妇女的意外怀孕率和相关因素。MethodsA横断面研究进行了招聘分层匹配的地理分布的艾滋病毒阳性的育龄妇女（18-52岁）生活在加拿大安大略。2007年10月至2009年4月期间从38个地点招募的妇女被邀请完成一项189项自我管理的调查。这项分析的重点是与怀孕有关的问题，以及最近一次怀孕是否有意为之。Logistic回归模型拟合计算未经调整和调整后的比值比的相关性发生意外怀孕后，艾滋病毒的诊断。幸福与意外怀孕也assessed.ResultsThe的中位年龄在416名参与HIV阳性的妇女谁是以前怀孕的调查（53%之前和47%后艾滋病毒诊断）的时间是38年[四分位距（IQR）33-44岁]，他们的最后一次怀孕的中位数为8年（IQR 3-14年）之前的调查（n = 283）。59%出生在加拿大境外，47%为非洲裔。在这416名妇女中，56%（95%置信区间（CI）51-61%）的人确定她们的最后一次怀孕是意外的（57%在艾滋病毒诊断之前，54%在艾滋病毒诊断之后）。在多变量模型中，HIV诊断后意外怀孕的显著相关因素是：婚姻状况（P = 0.01）和从未生育（P = 0.01）。妇女不太高兴，如果他们的怀孕是意外的（P = 0.01）。需要为这一人群制定怀孕计划，以减少胎儿和产妇并发症，并减少垂直和水平传播。
ObjectivesThere is speculation, but there are few data, on the high rates of unintended pregnancies in HIV-positive women. We investigated rates and correlates of unintended pregnancies among HIV-positive women of reproductive age.MethodsA cross-sectional study was conducted with recruitment stratified to match the geographical distribution of HIV-positive women of reproductive age (18-52 years) living in Ontario, Canada. Women, recruited from 38 sites between October 2007 and April 2009, were invited to complete a 189-item self-administered survey. This analysis focused on questions relating to pregnancy and whether the last pregnancy was intended. Logistic regression models were fitted to calculate unadjusted and adjusted odds ratios of correlates of unintended pregnancies occurring after HIV diagnosis. Happiness with unintended pregnancies was also assessed.ResultsThe median age at the time of the survey of the 416 participating HIV-positive women who were previously pregnant (53% before and 47% after HIV diagnosis) was 38 years [interquartile range (IQR) 33-44 years] and their last pregnancy was a median of 8 years (IQR 3-14 years) prior to the survey (n = 283). Fifty-nine per cent were born outside Canada and 47% were of African ethnicity. Of the 416, 56% [95% confidence interval (CI) 51-61%] identified that their last pregnancy was unintended (57% before and 54% after HIV diagnosis). In the multivariable model, significant correlates of unintended pregnancy after HIV diagnosis were: marital status (P = 0.01) and never having given birth (P = 0.01). Women were less happy if their pregnancy was unintended (P = 0.01).ConclusionsThe prevalence of unintended pregnancy was high in this cohort. Pregnancy planning programmes are needed for this population to decrease fetal and maternal complications and reduce vertical and horizontal transmission.