Recent advances in SPECT imaging
Recent advances in SPECT imaging
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DOI：
10.2967/jnumed.106.032680
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发表时间：
2007-04-01
影响因子：
9.3
通讯作者：
Madsen, Mark T.
中科院分区：
文献类型：
--
作者：
Madsen, Mark T.
SPECT是一个快速变化的领域，过去几年在硬件技术和图像处理算法方面都有了新的发展。在元件层面，半导体技术的应用也得到了改善，包括半导体放大器和光子传感器。这些设备允许制造更小和更紧凑的系统，可以针对特定应用进行定制。新的临床设备包括不使用传统准直的高计数灵敏度心脏SPECT系统和诊断质量混合SPECT/CT系统的引入。虽然重建算法已经取得了稳步进展，但令人兴奋的新处理算法已经商业化，有望在不牺牲诊断质量的情况下大幅减少SPECT采集时间。临床前小动物SPECT系统已成为核医学的主要焦点。这些系统将SPECT的极限推到了亚毫米范围，使其成为有价值的分子成像工具，能够提供其他模态无法提供的信息。
SPECT is a rapidly changing field, and the past several years have produced new developments in both hardware technology and image-processing algorithms. At the component level there have been improvements in scintillators and photon transducers as well as a greater availability of semiconductor technology. These devices permit the fabrication of smaller and more compact systems that can be customized for particular applications. New clinical devices include high-count sensitivity cardiac SPECT systems that do not use conventional collimation and the introduction of diagnostic-quality hybrid SPECT/CT systems. While there has been steady progress with reconstruction algorithms, exciting new processing algorithms have become commercially available that promise to provide substantial reductions in SPECT acquisition time without sacrificing diagnostic quality. Preclinical small-animal SPECT systems have become a major focus in nuclear medicine. These systems have pushed the limits of SPECT into the submillimeter range, making them valuable molecular imaging tools capable of providing information unavailable from other modalities.