VETERANS ADMINISTRATION-ARMY COOPERATIVE STUDY OF PULMONARY FUNCTION .1. CLINICAL SPIROMETRY IN NORMAL MEN
VETERANS ADMINISTRATION-ARMY COOPERATIVE STUDY OF PULMONARY FUNCTION .1. CLINICAL SPIROMETRY IN NORMAL MEN
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DOI：
10.1016/0002-9343(61)90096-1
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发表时间：
1961-01-01
影响因子：
5.9
通讯作者：
SYNER, JC
中科院分区：
文献类型：
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作者：
KORY, RC;BOREN, HG;SYNER, JC
本文介绍了退伍军人管理局-陆军肺功能测试协作组制定的临床肺量测定标准化程序。468名正常男性的肺功能研究由15个参与的肺功能实验室提供。测量的十九个参数被制成表格，并借助电子计算机进行分析。计算每次测量的平均值和标准偏差。构建了一个积矩相关矩阵，该矩阵显示了每个测量值与其他18个测量值的关系。在几个物理测量中，年龄和身高显示出与VC、FEV 0. 5、FEV 1. 0和MVVF的最高相关性。根据年龄和身高构建这些解释性测量的回归方程。本文提出了一种列线图，可用于同时获得VC、FEV0.5、FEV和NVVF的正常预测值。预测公式与两组独立数据的交叉验证表明，退伍军人管理局-陆军预测公式保留了其可靠性，并具有目前可用的任何公式的最高交叉验证系数。使用BSA在构建肺功能测定的预测公式隐含的弱点进行了讨论。
A standardized procedure for clinical spirometry is described which was formulated by a Veterans Administration-Army Cooperative Group for pulmonary function testing. Spirometric studies of 468 normal men were contributed by fifteen participating pulmonary function laboratories. The nineteen parameters measured were tabulated and analyzed with the aid of an electronic computer. Mean values and standard deviations were calculated for each measurement. A product-moment correlation matrix was constructed which shows the relationship of each measurement to the other eighteen measurements. Of the several physical measurements, age and height showed the highest correlations with VC, FEVo.5, FEVl.O and MVVF. Regression equations for these ventilatory measurements were constructed upon age and height. A nomogram is presented which can be used to obtain simultaneously the predicted normal values for VC, FEV0.5, FEV and NVVF. Cross validation of the prediction formulas with two sets of independent data demonstrates that the Veterans Administration-Army prediction formulas have retained their reliability and have the highest cross-validation coefficients of any formulas now available. The weakness implicit in the use of BSA in constructing prediction formulas for spirometric measurements is discussed.