Prevalence of vitamin D [25(OH)D] deficiency and effects of supplementation with ergocalciferol (vitamin D2) in stage 5 chronic kidney disease patients
Prevalence of vitamin D [25(OH)D] deficiency and effects of supplementation with ergocalciferol (vitamin D2) in stage 5 chronic kidney disease patients
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DOI：
10.1053/j.jrn.2008.04.008
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发表时间：
2008-07-01
影响因子：
3.2
通讯作者：
McCaffrey, Susan
中科院分区：
文献类型：
--
作者：
Blair, Debra;Byham-Gray, Laura;McCaffrey, Susan
目的：本研究调查了维生素D缺乏症的患病率，其与营养相关参数的相关性，以及5期慢性肾脏病（CKD）中补充麦角钙化醇的影响。感兴趣的措施包括血清白蛋白，糖化血红蛋白（HgA 1c），血红蛋白，磷，校正钙，甲状旁腺激素（iPTH），平衡的标准化蛋白分解代谢率（enPCR），和生活质量调查身体成分评分（SF-36 PCS）设计和设置：这项回顾性研究在马萨诸塞州西部的五个透析中心进行。2006年，在开始评估血清25（OH）D并在血清25（OH）D水平低于正常水平时实施麦角钙化醇治疗的方案后，对患者记录进行了为期6个月的检查。
Objective: This study investigated the prevalence of vitamin D deficiency, its association with nutrition-related parameters, and the effects of ergocalciferol supplementation in stage 5 chronic kidney disease (CKD). Measures of interest included serum albumin, glycosylated hemoglobin (HgA1c), hemoglobin, phosphorus, corrected calcium, parathyroid hormone (iPTH), equilibrated normalized protein catabolic rate (enPCR), and quality-of life-survey physical component score (SF-36 PCS).Design and Setting: This retrospective study was conducted at five dialysis centers in western Massachusetts. Patient records were examined for a 6-month period in 2006, after initiation of a protocol to assess serum 25(OH)D and implement treatment with ergocalciferol if the level of serum 25(OH)D were