High-Yielding One-Pot Synthesis of Glucose from Cellulose Using Simple Activated Carbons and Trace Hydrochloric Acid
High-Yielding One-Pot Synthesis of Glucose from Cellulose Using Simple Activated Carbons and Trace Hydrochloric Acid
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DOI：
10.1021/cs300845f
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发表时间：
2013-04-01
期刊：
影响因子：
12.9
通讯作者：
Fukuoka, Atsushi
中科院分区：
文献类型：
--
作者：
Kobayashi, Hirokazu;Yabushita, Mizuho;Fukuoka, Atsushi
利用简单的活性炭和0.012%的水中盐酸，实现了纤维素和戊糖/己糖的一锅高产葡萄糖合成。球磨纤维素和碳在反应前在固体底物和固体催化剂之间形成了良好的物理接触，选择性地、大幅度地提高了纤维素解聚成低聚物的速度。因此，我们的方法克服了这类反应的一个主要障碍，即固体催化剂和固体底物之间的碰撞是有限的。机理研究表明，碳的活性位点是弱酸性官能团，其中羧基和酚基协同作用于水解反应。
High-yielding one-pot synthesis of glucose from cellulose and pentoses/hexoses from real biomass is achieved by using simple activated carbons and 0.012% HCl in water. Ball-milling cellulose and the carbon together created good physical contact between the solid substrate and solid catalyst before the reaction, selectively and drastically improving the depolymerization rate of cellulose to oligomers. Thus, our methodology overcomes a major obstacle in this type of reaction, namely, that the collision between a solid catalyst and a solid substrate is limited. Mechanistic studies have suggested that the active sites of the carbons are weakly acidic functional groups, in which cicinal carboxylic and phenolic groups synergistically work for the hydrolysis reaction.