CLINICAL DEMONSTRATION THAT CATHETER-DELIVERED ULTRASOUND ENERGY REVERSES ARTERIAL VASOCONSTRICTION
CLINICAL DEMONSTRATION THAT CATHETER-DELIVERED ULTRASOUND ENERGY REVERSES ARTERIAL VASOCONSTRICTION
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DOI：
10.1016/0735-1097(92)90032-i
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发表时间：
1992-09-01
影响因子：
24
通讯作者：
CUMBERLAND, DC
中科院分区：
文献类型：
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作者：
SIEGEL, RJ;GAINES, P;CUMBERLAND, DC
目标.本研究旨在描述超声能量对导丝引起的动脉血管收缩的临床效果。我们以前已经表明，超声能量（20 kHz）提供的线探头产生剂量依赖性，内皮非依赖性平滑肌松弛能够逆转受体介导的和电压依赖性血管收缩在体外。使用高强度、低频超声导管系统对2例患者的股浅动脉完全闭塞进行再通。再通后，近端残余狭窄分别为
Objectives. This study was designed to describe the clinical effects of ultrasound energy on guide-wire-induced arterial vasoconstriction.Background. We have previously shown that ultrasound energy (20 kHz) delivered by a wire probe produces dose-dependent, endothelium-independent smooth muscle relaxation capable of reversing both receptor-mediated and voltage-dependent vasoconstriction in vitro.Methods. A high intensity, low frequency ultrasound catheter system was used to recanalize total occlusions in the superficial femoral arteries of two patients. After recanalization, the proximal residual stenoses were each