Secular Trends in Helicobacter pylori Seroprevalence in Adults in the United States: Evidence for Sustained Race/Ethnic Disparities
Secular Trends in Helicobacter pylori Seroprevalence in Adults in the United States: Evidence for Sustained Race/Ethnic Disparities
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DOI：
10.1093/aje/kwr288
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发表时间：
2012-01-01
影响因子：
5
通讯作者：
Aiello, Allison E.
中科院分区：
文献类型：
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作者：
Grad, Yonatan H.;Lipsitch, Marc;Aiello, Allison E.
参加连续国家健康和营养检查调查的美国成年人幽门螺杆菌血清阳性率水平（1999-2000年）在所有种族/族裔群体中随着年龄的增长而增加，墨西哥裔美国人的年龄标准化水平明显更高（64.0%，95%置信区间（CI）：58.8，69.2）和非西班牙裔黑人（52.0%，95% CI：48.3，55.7）与非西班牙裔白人（21.2%，95% CI：19.1，23.2）相比。尽管血清阳性率水平与1988年至1991年在非西班牙裔黑人和墨西哥裔美国人中进行的全国健康和营养检查调查中发现的水平相似，但非西班牙裔白人的血清阳性率明显较低，特别是在老年人中。导致H.幽门螺杆菌血清阳性率似乎优先作用于非西班牙裔白色人群。
Helicobacter pylori seroprevalence levels in US adults participating in the continuous National Health and Nutrition Examination Survey (1999-2000) increased with age in all racial/ethnic groups, with significantly higher age-standardized levels in Mexican Americans (64.0%, 95% confidence interval (CI): 58.8, 69.2) and non-Hispanic blacks (52.0%, 95% CI: 48.3, 55.7) compared with non-Hispanic whites (21.2%, 95% CI: 19.1, 23.2). Although seroprevalence levels remained similar to those found in National Health and Nutrition Examination Surveys from 1988 to 1991 among non-Hispanic blacks and Mexican Americans, they were significantly lower in non-Hispanic whites, especially at older ages. The factors driving the decline in H. pylori seroprevalence appear to be acting preferentially on the non-Hispanic white population.