Strategies to improve adherence to recommended chloroquine treatment regimes: a quasi-experiment in the context of integrated primary health care delivery in Ghana

Strategies to improve adherence to recommended chloroquine treatment regimes: a quasi-experiment in the context of integrated primary health care delivery in Ghana
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DOI:
10.1016/s0277-9536(01)00366-5
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发表时间:
2002-12-01
影响因子:
5.4
通讯作者:
Evans, D
Evans, D
中科院分区:
医学2区
文献类型:
--
作者:
Agyepong, IA;Ansah, E;Evans, D

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本文介绍了一项干预研究的结果进行的一部分,在加纳的农村地区负责综合初级卫生保健服务的地区健康管理小组的活动。其目的是测试改善向患者提供的信息和药物标签的组合对坚持推荐的抗疟疾治疗方案的影响,重点是口服氯喹,用于急性无并发症疟疾的门诊管理。本研究采用准实验前测后测对照组设计,部分随机分配临床。结果表明,干预措施改善了向客户提供氯喹处方的信息流,并改善了干预地区疟疾急性临床发作家庭治疗药物的标签。所有诊所的依从性都有所改善。然而,在干预开始时表现最差的诊所中,依从性的改善最为明显。结果的影响,以提高坚持氯喹治疗门诊的基础上进行了讨论。(C)2002爱思唯尔科技有限公司。保留所有权利。
This paper presents the results of an intervention study carried out as part of the activities of a District Health Management Team responsible for integrated primary health care delivery in a rural district in Ghana. The aim was to test the impact of a combination of improved information provision to patients and drug labeling on adherence to recommended anti-malarial treatment regimens focusing on oral chloroquine, for the outpatient management of acute uncomplicated malaria. The study had a quasi-experimental pre-test post-test control group design with partly random allocation by clinic. The results show that the intervention resulted in an improved flow of information to clients prescribed chloroquine, and better labeling of drugs for the home treatment of acute clinical episodes of malaria in the intervention area. Improvements in adherence occurred in all clinics. However, improvements in adherence were most marked in the clinic that was worst performing at the start of the intervention. Implications of the results for improving adherence to chloroquine therapy on an outpatient basis are discussed. (C) 2002 Elsevier Science Ltd. All rights reserved.