Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature

Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature
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DOI:
10.1016/j.ajog.2005.08.057
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发表时间:
2006-08-01
影响因子:
9.8
通讯作者:
Romero, Roberto
Romero, Roberto
中科院分区:
医学1区
文献类型:
--
作者:
Haddad, Ramsi;Tromp, Gerard;Romero, Roberto

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目的:本研究的目的是确定哪些生物过程可能参与正常分娩。研究设计:从足月无产程(TNL)和产程(TIL)患者中提取绒毛膜羊膜(n = 24)和血液(n = 20)的转录谱。结果:197个转录本的表达(P
Objective: The purpose of this study was to identify which biological processes may be involved in normal labor.Study design: Transcriptional profiles for chorioamniotic membranes (n = 24) and blood (n = 20) were generated from patients at term with no labor (TNL) and in labor (TIL).Results: Expression of 197 transcripts (P