Influence of Magnetic Field Strength on Magnetic Resonance Imaging Radiomics Features in Brain Imaging, an In Vitro and In Vivo Study.
Influence of Magnetic Field Strength on Magnetic Resonance Imaging Radiomics Features in Brain Imaging, an In Vitro and In Vivo Study.
复制标题
磁场强度对脑成像，体外和体内研究中磁共振成像放射素学特征的影响。
DOI：
10.3389/fonc.2020.541663
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发表时间：
2020
影响因子：
4.7
通讯作者：
Bidault F
中科院分区：
文献类型：
--
作者：
Ammari S;Pitre-Champagnat S;Dercle L;Chouzenoux E;Moalla S;Reuze S;Talbot H;Mokoyoko T;Hadchiti J;Diffetocq S;Volk A;El Haik M;Lakiss S;Balleyguier C;Lassau N;Bidault F
定量成像生物标志物（放射组学）的发展和临床应用已经确立了识别改变放射组学再现性的参数的需求。本研究旨在评估磁场强度对神经放射学临床实践中磁共振成像（MRI）放射组学特征的影响。使用两种不同的磁场（1.5和3T），使用同一制造商的两种临床MR设备，在两个体模和10名健康志愿者上采集T1 3D SPGR序列。钆的浓度和质地的异质性方面的差异。使用LIFEX软件分割27个感兴趣区域（体模：21个，志愿者：6个）。分析了34个特征。在体模数据集中，当在1.5T或3T下测量时，15个放射组学特征中的10个（67%）显著不同（学生t检验，p < 0.05）。灰度值的变化和像素大小对纹理特征也有一定的影响。这些发现在健康志愿者中得到了验证。根据临床检查的日常使用方案，在评价纹理特征时，在1.5T上提取的放射组学特征不应与3T互换使用。当将研究结果调整到不同的平台或设计多中心试验时，应调整此类混杂因素。
The development and clinical adoption of quantitative imaging biomarkers (radiomics) has established the need for the identification of parameters altering radiomics reproducibility. The aim of this study was to assess the impact of magnetic field strength on magnetic resonance imaging (MRI) radiomics features in neuroradiology clinical practice. T1 3D SPGR sequence was acquired on two phantoms and 10 healthy volunteers with two clinical MR devices from the same manufacturer using two different magnetic fields (1.5 and 3T). Phantoms varied in terms of gadolinium concentrations and textural heterogeneity. 27 regions of interest were segmented (phantom: 21, volunteers: 6) using the LIFEX software. 34 features were analyzed. In the phantom dataset, 10 (67%) out of 15 radiomics features were significantly different when measured at 1.5T or 3T (student’s t-test, p < 0.05). Gray levels resampling, and pixel size also influence part of texture features. These findings were validated in healthy volunteers. According to daily used protocols for clinical examinations, radiomic features extracted on 1.5T should not be used interchangeably with 3T when evaluating texture features. Such confounding factor should be adjusted when adapting the results of a study to a different platform, or when designing a multicentric trial.
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影响因子：
5.9
作者：
Savadjiev, Peter;Chong, Jaron;Gallix, Benoit
通讯作者：
Gallix, Benoit
影响因子：
4.6
作者：
Leger S;Zwanenburg A;Pilz K;Lohaus F;Linge A;Zöphel K;Kotzerke J;Schreiber A;Tinhofer I;Budach V;Sak A;Stuschke M;Balermpas P;Rödel C;Ganswindt U;Belka C;Pigorsch S;Combs SE;Mönnich D;Zips D;Krause M;Baumann M;Troost EGC;Löck S;Richter C
通讯作者：
Richter C
影响因子：
2.1
作者：
Moradmand, Hajar;Aghamir, Seyed Mahmood Reza;Ghaderi, Reza
通讯作者：
Ghaderi, Reza
影响因子：
2.5
作者：
Collewet, G;Strzelecki, M;Mariette, F
通讯作者：
Mariette, F
影响因子：
2.4
作者：
Chirra, Prathyush;Leo, Patrick;Viswanath, Satish E.
通讯作者：
Viswanath, Satish E.