Overexpression of the endoplasmic reticulum chaperone BiP3 regulates XA21-mediated innate immunity in rice.
Overexpression of the endoplasmic reticulum chaperone BiP3 regulates XA21-mediated innate immunity in rice.
复制标题
DOI:
10.1371/journal.pone.0009262
复制
发表时间:
2010-02-17
期刊:
影响因子:
3.7
通讯作者:
Ronald PC
中科院分区:
文献类型:
--
作者:
Park CJ;Bart R;Chern M;Canlas PE;Bai W;Ronald PC
Recognition of pathogen-associated molecular patterns by pattern recognition receptors (PRRs) activates the innate immune response. Although PRR-mediated signaling events are critical to the survival of plants and animals, secretion and localization of PRRs have not yet been clearly elucidated. Here we report the in vivo interaction of the endoplasmic reticulum (ER) chaperone BiP3 with the rice XA21 PRR, which confers resistance to the Gram negative bacterium, Xanthomonas oryzae pv. oryzae (Xoo). We show that XA21 is glycosylated and is primarily localized to the ER and also to the plasma membrane (PM). In BiP3-overexpressing rice plants, XA21-mediated immunity is compromised, XA21 stability is significantly decreased, and XA21 proteolytic cleavage is inhibited. BiP3 overexpression does not affect the general rice defense response, cell death or brassinolide-induced responses. These results indicate that BiP3 regulates XA21 protein stability and processing and that this regulation is critical for resistance to Xoo.
登录
查看更多内容
影响因子:
5.1
作者:
Bart R;Chern M;Park CJ;Bartley L;Ronald PC
通讯作者:
Ronald PC
影响因子:
64.8
作者:
Chinchilla, Delphine;Zipfel, Cyril;Boller, Thomas
通讯作者:
Boller, Thomas
影响因子:
11.6
作者:
Gómez-Gómez, L;Bauer, Z;Boller, T
通讯作者:
Boller, T
影响因子:
64.5
作者:
通讯作者:
--
影响因子:
16
作者:
Jin, Hua;Yan, Zhenyan;Li, Jianming
通讯作者:
Li, Jianming