Brain communication in a completely locked-in patient using bedside near-infrared spectroscopy.
Brain communication in a completely locked-in patient using bedside near-infrared spectroscopy.
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DOI：
10.1212/wnl.0000000000000449
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发表时间：
2014-05-27
期刊：
影响因子：
9.9
通讯作者：
Birbaumer N
中科院分区：
文献类型：
--
作者：
Gallegos-Ayala G;Furdea A;Takano K;Ruf CA;Flor H;Birbaumer N
肌萎缩性侧索硬化症（ALS）可导致闭锁状态（LIS），其特征为麻痹，最终呼吸衰竭，通过人工通气进行补偿，1或完全LIS（CLIS），伴有额外的眼肌完全麻痹。脑机接口（BCI）已被用于使瘫痪的人重新获得基本的通信，2虽然目前基于EEG的BCI没有成功与CLIS患者。3我们提出了IV类病例证据，以建立在CLIS中的通信是可能的基于近红外光谱（NIRS）的代谢BCI。
Amyotrophic lateral sclerosis (ALS) can result in the locked-in state (LIS), characterized by paralysis, and eventual respiratory failure, compensated by artificial ventilation,1 or the completely LIS (CLIS), with additional total paralysis of eye muscles. Brain–computer interfaces (BCIs) have been used to allow paralyzed people to regain basic communication,2 although current EEG-based BCIs have not succeeded with CLIS patients.3 We present Class IV case evidence to establish that communication in the CLIS is possible with a metabolic BCI based on near-infrared spectroscopy (NIRS).