The association of actigraphy-assessed sleep duration with sleep blood pressure, nocturnal hypertension, and nondipping blood pressure: the coronary artery risk development in young adults (CARDIA) study.
The association of actigraphy-assessed sleep duration with sleep blood pressure, nocturnal hypertension, and nondipping blood pressure: the coronary artery risk development in young adults (CARDIA) study.
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DOI：
10.1097/hjh.0000000000002956
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发表时间：
2021-12-01
影响因子：
4.9
通讯作者：
Muntner P
中科院分区：
文献类型：
--
作者：
Abdalla M;Sakhuja S;Akinyelure OP;Thomas SJ;Schwartz JE;Lewis CE;Shikany JM;Lloyd-Jones D;Booth JN 3rd;Shimbo D;Hall MH;Muntner P
夜间高血压和非下降收缩压（SBP）与心血管疾病（CVD）风险增加有关。短睡眠时间和长睡眠时间（SSD和LSD）也与心血管疾病风险增加有关，并且可能是夜间高血压和非下降型收缩压的危险因素。我们在2015-2016年完成24小时动态血压监测、腕动记录和睡眠日记的647名白色和非洲裔美国人年轻人冠状动脉风险发展（CARDIA）研究参与者中，研究了SSD和LSD与睡眠血压、夜间高血压和非下降型SBP之间的相关性。参与者入睡和清醒的时间由活动记录仪和睡眠日记确定。夜间高血压定义为睡眠血压≥120/70 mmHg，非降压型SBP定义为平均睡眠-清醒SBP比值>0.90。睡眠时间分为SSD（<6小时）、正常睡眠时间（NSD：6-8.9小时）和LSD（≥ 9小时）。SSD和LSD的患病率分别为13.9%和21.1%。与NSD受试者相比，LSD受试者的平均睡眠SBP（2.1 mmHg，95%置信区间[CI] 0.2，4.1 mmHg）和舒张压（1.7 mmHg，95% CI 0.5，3.0 mmHg）较高。与NSD受试者相比，LSD受试者夜间高血压（患病率比[PR]：1.26，95% CI 1.03-1.54）和非下降SBP（PR 1.33，95% CI 1.03-1.72）的患病率更高。没有证据表明SSD与睡眠SBP或DBP、夜间高血压或非下降SBP之间存在关联。这些结果表明，LSD可能与夜间高血压和非下降SBP。
Nocturnal hypertension and non-dipping systolic blood pressure (SBP) are associated with increased cardiovascular disease (CVD) risk. Short and long sleep duration (SSD and LSD) are also associated with increased CVD risk and may be risk factors for nocturnal hypertension and non-dipping SBP. We examined the association between SSD and LSD with sleep BP, nocturnal hypertension, and non-dipping SBP among 647 white and African American Coronary Artery Risk Development in Young Adults (CARDIA) study participants who completed 24-hour ambulatory BP monitoring, wrist actigraphy, and sleep diaries in 2015-2016. The times when participants were asleep and awake were determined from actigraphy complemented by sleep diaries. Nocturnal hypertension was defined as sleep BP ≥120/70 mmHg and non-dipping SBP as mean sleep-to-awake SBP ratio >0.90. Sleep duration was categorized as SSD (<6 hours), normal sleep duration (NSD: 6-8.9 hours), and LSD (≥ 9 hours). The prevalence of SSD and LSD were 13.9% and 21.1%, respectively. Compared to participants with NSD, participants with LSD had higher mean sleep SBP (2.1 mmHg, 95% confidence interval [CI] 0.2, 4.1 mmHg) and diastolic BP (1.7 mmHg, 95% CI 0.5, 3.0 mmHg). Participants with LSD had a higher prevalence of nocturnal hypertension (prevalence ratio [PR]: 1.26, 95% CI 1.03-1.54) and non-dipping SBP (PR 1.33, 95% CI 1.03-1.72) compared to participants with NSD. There was no evidence of an association between SSD and sleep SBP or DBP, nocturnal hypertension, or non-dipping SBP. These findings suggest that LSD may be associated with nocturnal hypertension and non-dipping SBP.