Relevance of sleep quality on caregiver burden in Parkinson's disease
Relevance of sleep quality on caregiver burden in Parkinson's disease
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DOI：
10.1007/s10072-018-3252-2
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发表时间：
2018-05-01
影响因子：
3.3
通讯作者：
Antonini, Angelo
中科院分区：
文献类型：
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作者：
Bartolomei, Luigi;Pastore, Andrea;Antonini, Angelo
帕金森病是一种影响患者及其家庭生活质量的神经退行性疾病。80-90%的帕金森病患者出现睡眠障碍，对帕金森病患者的幸福感有很大影响。我们调查了患者的睡眠质量和抑郁对其照顾者的负担、情绪、生活质量和睡眠质量的关系。进行了一项多中心、地区性(威尼托)观察性横断面研究，包括55对患者-照顾者。采用帕金森氏病睡眠评定量表(PDSS)和爱普沃斯嗜睡量表(ESS)评定睡眠障碍，贝克抑郁量表(BDI)评定抑郁，帕金森病问卷(PDQ-39)评定生活质量。照顾者的评估采用照顾者负担问卷(CBI)，BDI，SF-36健康调查作为HRQL的衡量标准，医疗结果研究-睡眠量表(MOS-SS)衡量睡眠质量。CBI、HRQOL、MOS-SS和BDI评分与患者的年龄、认知(简易智力状态检查(MMSE)和正面评估成套测验(FAB))、病程、Hoehn和Yahr(H&Y)以及UPDRS III评分无关，而与患者的睡眠质量、抑郁和生活质量显著相关。脑功能指数和心率生活质量与患者的内分泌症状评分和L-多巴的日剂量相关。这项研究强调了患者和照顾者的生活质量之间存在着重要的关系。有趣的是，睡眠质量和抑郁比运动障碍更能预测照顾者的幸福感。
Parkinson's disease (PD) is a neurodegenerative disorder which affects the quality of life of patient and their family. Sleep disorders appear in 80-90% of PD patients and have a great impact on the PD well-being. We examined the relationship of patients' sleep quality and depression on burden, mood, quality of life, and quality of sleep of their caregivers. A multicenter, regional (Veneto), observational, cross-sectional study that included 55 patient-caregiver pairs was conducted. Patients were assessed using Parkinson's Disease Sleep Scale (PDSS) and Epworth Sleepiness Scale (ESS) for sleep disorders, Beck Depression Inventory (BDI) as a measure of depression, and Parkinson's Disease Questionnaire (PDQ-39) as a measure of quality of life. Caregivers were evaluated by the Caregiver Burden Inventory (CBI) a measure of burden, BDI, SF-36 Health Survey as measures of HRQoL, and Medical Outcomes Study-Sleep Scale (MOS-SS) for quality of sleep. CBI, HRQoL, MOS-SS, and BDI scores displayed no association with patients' age, cognition (Mini Mental State Examination (MMSE) and Frontal Assessment Battery (FAB)), disease duration, and Hoehn and Yahr (H&Y), and UPDRS III scales whereas were significantly correlated with patients' quality of sleep, depression, and quality life. CBI and HRQoL were also associated respectively with patients' ESS and l-dopa daily dose. This study underscores the presence of a significant relationship between patient and caregiver quality of life. Interestingly, sleep quality and depression rather than motor disability best predicted caregivers' well-being.