Delaying decline in pulmonary function with physical activity - A 25-year follow-up

Delaying decline in pulmonary function with physical activity - A 25-year follow-up
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DOI:
10.1164/rccm.200208-954oc
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发表时间:
2003-08-15
影响因子:
24.7
通讯作者:
Nissinen, A
Nissinen, A
中科院分区:
医学1区
文献类型:
--
作者:
Pelkonen, M;Notkola, IL;Nissinen, A

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体育活动对健康的重要性已得到公认,但体育活动对肺功能的影响却知之甚少。我们研究了在七国研究中芬兰西南部农村队列中,体力活动是否可以减缓肺功能的下降。体力活动是通过每天步行、骑自行车和滑雪的公里数来估计的。我们有429名男性10年、275名男性20年和186名男性25年的完整数据。在最初的10年中,基线体力活动最高三分位数的男性FEV下降比最低三分位数的男性少9.8 ml/年。根据20年或25年的平均体力活动,最高三分位数的男性也失去了较少的肺功能(分别为p = 0.009和p = 0.043)。在所有吸烟类别中观察到类似的有益效果。在死亡率分析中,持续的高体力活动和活动增加到高水平与较低的死亡率相关。总之,结果表明,体力活动与肺功能下降较慢和死亡率较低有关,因此,应鼓励中老年人享受锻炼。
The importance of physical activity for health is well recognized, but little is known about the influence of physical activity on pulmonary function. We have examined whether physical activity could slow down the decline in pulmonary function among the southwestern rural Finnish cohort of the Seven Countries Study. Physical activity was estimated by kilometers walked, cycled, and skied daily. We had complete data for 429 men for 10 years, 275 men for 20 years, and 186 men for 25 years. During the first 10 years, the decline in FEV was 9.8ml/year less among men in the highest tertile of baseline physical activity than in men in the lowest tertile. According to the mean physical activity over either 20 or 25 years, men in the highest tertile also lost less pulmonary function (p = 0.009 and p = 0.043, respectively). A similar beneficial effect was observed in all smoking categories. In mortality analysis, continued high physical activity and an increase in activity to high level were associated with lower mortality. In conclusion, results indicated that physical activity is associated with a slower decline in pulmonary function and with lower mortality, and thus, middle-aged and older people should be encouraged to enjoy exercise.