SLEEP EEG SPECTRAL-ANALYSIS IN A DIURNAL RODENT - EUTAMIAS-SIBIRICUS
SLEEP EEG SPECTRAL-ANALYSIS IN A DIURNAL RODENT - EUTAMIAS-SIBIRICUS
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DOI：
10.1007/bf00619195
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发表时间：
1989-01-01
影响因子：
2.1
通讯作者：
DAAN, S
中科院分区：
文献类型：
--
作者：
DIJK, DJ;DAAN, S
1.在白天活动的啮齿类动物Eutamias sibiricus中研究了睡眠，长期植入EEG和EMG电极。分析24小时内（LD 12：12）的觉醒、非快速眼动（NREZM）睡眠和快速眼动（REM）睡眠的分布表明，在12小时光照期和12小时黑暗期，总睡眠时间分别占记录时间的27.5%和74.4%。睡眠脑电图的频谱分析显示，在黑暗中的NREM睡眠中的δ功率密度进行性衰减。黑暗结束时，高频功率密度增加。在光照条件下，高频功率密度降低，低频功率密度增加。2.分析了三种不同光周期（LD 18：6、12：12、6：18）下的警戒状态分布，发现昼长的变化主要导致了睡眠和觉醒在光照和黑暗下的重新分配。在长时间的白天，在光照下睡眠的百分比增加。长日照时NREM睡眠δ功率密度的时程呈现上升段长、下降段短的特点，短日照时则呈现相反的过程。因此，在长日照下，光照期间的功率密度相对较高。3.强迫活动剥夺睡眠24 h后，觉醒和NREM睡眠的百分比无明显变化，而REM睡眠略有增强。脑电图功率密度，然而，显着增加了约。在恢复睡眠的前3小时内，50%在1.25-10.0 Hz范围内。这种增长在恢复的夜晚逐渐衰减。4.同样的24小时睡眠剥夺技术导致了一个约。在恢复期间，氧气消耗量增加25%。虽然EEG频谱分析的结果与Δ功率密度反映了NREM睡眠的“强度”的假设是一致的，因为先前的觉醒增强了NREM睡眠，并且先前的睡眠降低了NREM睡眠的强度，但是睡眠剥夺后这种增强的睡眠深度与睡眠功能假设的能量守恒所预期的能量消耗降低无关。
1. Sleep was studied in the diurnal rodent Eutamias sibiricus, chronically implanted with EEG and EMG electrodes. Analysis of the distribution of wakefulness, nonrapid eye movement (NREZM) sleep, and rapid eye movement (REM) sleep over the 24 h period (LD 12:12) showed that total sleep time was 27.5% of recording time during the 12 h light period and 74.4% during the 12 h dark period. Spectral analysis of the sleep EEG revealed a progressive decay in delta power density in NREM sleep during darkness. Power density of the highe r frequencies increased at the end of darkness. Power density of the higher frequencies decreased and that of the lower frequencies increased during light. 2. Analysis of the distribution of vigilance states under three different photoperiods (LD 18:6, 12:12; 6:18) revealed that changes in daylength mainly resulted in a redistribution of sleep and wakefulness over light and darkness. Under long days the percentage of sleep during light was enhanced. The time course of delta power density in NREM sleep was characterized by a long rising part and a short falling part under long days, while a reversed picture emerged under short days. As a consequence, the power density during light was relatively high under long days. 3. After 24 h sleep deprivation by forced activity, no significant changes in the pecentage of wakefulness and NREM were observed, whereas REM sleep was slightly enhanced. EEG power density, however, was significantly increased by ca. 50% in the 1.25-10.0 Hz range in the first 3 h of recovery sleep. This increase gradually decayed over the recovery night. 4. The same 24 h sleep deprivation technique led to a ca. 25% increase in oxygen consumption during recovery nights. While the results of the EEG spectral analysis are compatible with the hypothesis that delta power density reflects the ''intensity'' of NREM sleep as enhanced by prior wakefulness and reduced by prior sleep, such enhanced sleep depth after sleep deprivation is not associated with reduced energy expenditure as might be anticipated by some energy conservation of hypotheses on sleep function.