Results of catheter ablation of atrial fibrillation in hypertrophied hearts Comparison between primary and secondary hypertrophy
Results of catheter ablation of atrial fibrillation in hypertrophied hearts Comparison between primary and secondary hypertrophy
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DOI：
10.1016/j.jjcc.2014.07.005
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发表时间：
2015-05-01
影响因子：
2.5
通讯作者：
Hindricks, Gerhard
中科院分区：
文献类型：
--
作者：
Muessigbrodt, Andreas;Kosiuk, Jedrzej;Hindricks, Gerhard
背景和目的：大约20-25%的肥厚型心肌病（HCM）患者在疾病的临床过程中发生房颤（AF），这一比例明显高于一般人群。本研究的目的是报告AF患者的手术结果，无论是原发性或继发性左心室肥厚（LVH）。方法和科目：22个连续HCM患者。(55将2009年9月至2012年7月期间接受AF消融术的症状性AF患者（男性，平均年龄57 ± 8岁）的手术结局和随访特征与我们前瞻性AF导管消融登记研究中的22例匹配的继发性心脏肥大对照（64%男性，63 ± 10岁）进行比较。结果与结论：射频导管消融术（RFCA）成功地恢复了HCM和继发性LVH患者的长期窦性心律。然而，HCM患者需要更多的RFCA手术和经常额外的抗心律失常药物治疗，以维持窦性心律。(C)2014年日本心脏病学院。由爱思唯尔有限公司出版。保留所有权利。
Background and purpose: Approximately 20-25% of the patients with hypertrophic cardiomyopathy (HCM) develop atrial fibrillation (AF) during the clinical course of the disease, a percentage significantly larger than that of the general population. The purpose of the present study was to report on the procedural results of patients with AF and either primary or secondary left ventricular hypertrophy (LVH).Methods and subjects: Twenty-two consecutive HCM patients. (55% male, mean age 57 +/- 8 years) with symptomatic AF, having undergone AF ablation procedures between September 2009 and July 2012 were compared with respect to procedural outcome and follow-up characteristics with 22 matched controls with secondary cardiac hypertrophy (64% male, 63 +/- 10 years) from our prospective AF catheter ablation registry. Results and conclusion: Radiofrequency catheter ablation (RFCA) was successful in restoring long-term sinus rhythm in patients with LVH due to HCM and due to secondary etiology. However, patients with HCM needed more RFCA procedures and frequently additional antiarrhythmic drug therapy in order to maintain sinus rhythm. (C) 2014 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.