Quality of life in dementia patients in Athens, Greece: predictive factors and the role of caregiver-related factors
Quality of life in dementia patients in Athens, Greece: predictive factors and the role of caregiver-related factors
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DOI：
10.1017/s1041610210001262
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发表时间：
2011-04-01
影响因子：
7
通讯作者：
Mavreas, Venetsanos G.
中科院分区：
文献类型：
--
作者：
Mougias, Antonis A.;Politis, Antonis;Mavreas, Venetsanos G.
背景：生活质量（QOL）越来越被认为是当前痴呆症护理的主要目标。它的评估在痴呆症领域呈指数级增长，但很少有研究考虑照顾者变量来检验生活质量的预测因素。我们检查了与痴呆患者生活质量相关的患者和护理人员因素。方法：研究设计是横断面的。采访了 161 对社区痴呆症患者夫妇及其主要照顾者。生活质量通过 ADRQL 进行测量，这是一种代理评级的、针对痴呆症的生活质量工具。收集人口统计因素并使用经过验证的量表评估临床特征。结果：在单变量分析中，一些患者和护理人员的特征似乎与患者的生活质量相关。在多变量分析中，患者生活质量较差的独立预测因素是痴呆患者的行为和抑郁症状、对日常生活基本活动的依赖、较差的认知功能、抗精神病药物的使用、护理人员的负担以及护理人员不是成年子女。最终七因素模型的调整后 R-2 为 0.598。结论：痴呆症患者的生活质量是一个复杂的问题，与多个患者和护理人员因素相关。患者和护理人员都应努力改善患者的生活质量。如果可能，生活质量的测量应作为标准测量工具纳入日常痴呆症临床实践中。
Background: Quality of life (QOL) is increasingly recognized as the main target of currently available dementia care. Its assessment has grown exponentially in the dementia field, but few studies have examined predictive factors for QOL taking caregiver variables into account. We examined patient and caregiver factors related to the QOL of dementia patients.Methods: The study design was cross-sectional. 161 couples of community residing dementia patients and their primary caregivers were interviewed. QOL was measured by the ADRQL, a proxy-rated, dementia-specific QOL instrument. Demographic factors were collected and clinical characteristics assessed using validated scales.Results: In univariate analyses several patient and caregiver characteristics appeared associated with patient QOL. In multivariate analyses, independent predictors of worse patient QOL were behavioral and depressive symptoms of dementia patients, dependency in basic activities of daily living, poorer cognitive function, use of antipsychotic medication, caregiver burden, and caregiver not being an adult child. The adjusted R-2 of the final, seven-factor model was 0.598.Conclusions: QOL for a person with dementia is a complex issue that is associated with several patient and caregiver factors. Efforts to improve patients' QOL should be addressed for both patients and caregivers. The measurement of QOL should be included, when possible, as a standard measurement tool, in everyday dementia clinical practice.