Allergic rhinitis: indicators of quality of life

Allergic rhinitis: indicators of quality of life
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DOI:
10.1590/s1806-37132010000100017
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发表时间:
2010-02-01
影响因子:
2.7
通讯作者:
Solé, Dirceu
Solé, Dirceu
中科院分区:
医学4区
文献类型:
--
作者:
Camelo-Nunes, Inês Cristina;Solé, Dirceu

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本综述的目的是提供变应性鼻炎和生活质量损害之间关系的证据。数据来源是1997年至2008年期间录入Medline和LILACS数据库的原始文章、综述和共识声明。使用以下检索词:"过敏性鼻炎"、"生活质量"和"睡眠障碍"。过敏性鼻炎患者的生活质量通常会受到损害,这是由于该疾病的典型症状(打喷嚏、瘙痒、流涕和鼻塞)。此外,过敏性鼻炎的病理生理学经常扰乱睡眠,导致疲劳、易怒、记忆缺陷、白天嗜睡和抑郁。这种疾病的总负担超出了身体和社会功能的损害。它也有经济影响,当我们考虑到过敏性鼻炎是哮喘和鼻窦炎等合并症的可能病因时,这种影响变得更大。鼻塞是最突出的症状,与睡眠障碍有关,这可能对心理健康,学习,行为和注意力产生深远的影响。最后,过敏性鼻炎是一种影响成人、青少年和儿童的慢性疾病,通常诊断不足或治疗不当。过敏性鼻炎相关的睡眠障碍对患者进行日常生活活动的能力的有害影响是该疾病发病率的重要组成部分。有了准确的诊断,有各种可用的治疗方法,可以减少过敏性鼻炎的负担。
The objective of this review was to present evidence of the relationship between allergic rhinitis and impairment of quality of life. The data sources were original articles, reviews and consensus statements entered into the Medline and LILACS databases between 1997 and 2008. The following search terms were used: "allergic rhinitis"; "quality of life"; and "sleep disorders". Quality of life is often impaired in patients with allergic rhinitis, due to the classic symptoms of the disease (sneezing, pruritus, rhinorrhea and nasal obstruction). In addition, the pathophysiology of allergic rhinitis often disrupts sleep, leading to fatigue, irritability, memory deficits, daytime sleepiness and depression. The total burden of this disease goes beyond impairment of physical and social functioning. It has also a financial impact, which becomes greater when we consider the evidence that allergic rhinitis is a possible causal factor of comorbidities, such as asthma and sinusitis. Nasal obstruction, the most prominent symptom, is associated with sleep disorders, which can have a profound effect on mental health, learning, behavior and attention. Finally, allergic rhinitis-a chronic condition that affects adults, adolescents and children-is often underdiagnosed or inadequately treated. The deleterious impact that allergic rhinitis-related sleep disorders have on patient capacity to perform activities of daily living is an important component of the morbidity of the disease. With an accurate diagnosis, there are various available treatments that can reduce the burden of allergic rhinitis.