Intramolecular fluorescence resonance energy transfer in a novel PDI-BODIPY dendritic structure: Synthesis, Hg2+ sensor and living cell imaging

Intramolecular fluorescence resonance energy transfer in a novel PDI-BODIPY dendritic structure: Synthesis, Hg2+ sensor and living cell imaging
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新型 PDI–BODIPY 树突结构中的分子内荧光共振能量转移:合成、Hg2 传感器和活细胞成像

DOI:
10.1016/j.snb.2015.04.086
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发表时间:
2015-11-01
影响因子:
8.4
通讯作者:
Qian, Ying
Qian, Ying
中科院分区:
化学1区
文献类型:
--
作者:
Cheng, Huan-ren;Qian, Ying

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A novel intramolecular fluorescence resonance energy transfer (FRET) and photo-induced electron transfer (PET) based dendritic compound PDI-BODIPY has been developed: Tetra-boron-dipyrrin (BODIPY) attached perylene bisimide by click chemistry. Compound PDI-BODIPY as a fluorescence probe for rapid, selective, and sensitive determination of Hg(II) ions has 98% of high energy transfer efficiency. The dissociation constant (K-d) of the probe PDI-BODIPY with Hg2+ is 6.67 x 10(-12) M and the detection limit estimated from the titration results was 2 x 10(-8) M. Moreover, the imaging of Hg(II) ions in Hela cells further certified the potential value of the probe. (C) 2015 Elsevier B.V. All rights reserved.