Effect of spatial attention on human sensorimotor integration studied by transcranial magnetic stimulation
Effect of spatial attention on human sensorimotor integration studied by transcranial magnetic stimulation
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DOI：
10.1016/j.clinph.2004.12.006
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发表时间：
2005-05-01
影响因子：
4.7
通讯作者：
Nagamine, T
中科院分区：
文献类型：
--
作者：
Kotb, MA;Mima, T;Nagamine, T
目的：最近的经颅磁刺激（TMS）研究表明，感觉输入可以降低运动皮层的兴奋性（传入抑制）。为了阐明注意力对感觉运动整合的影响，我们研究了空间注意力对传入抑制的影响。方法：在 3 种情况下，对 9 名受试者进行右侧正中神经电刺激，以不同的延迟（10-300 毫秒），通过 TMS 对左侧运动皮层进行电刺激；结果：运动诱发电位的抑制发生在刺激间隔为 20 和 100 ms 时，其中右手空间注意比左手空间注意更明显。结论：受刺激侧空间注意引起的传入抑制增强可能反映了注意与感觉运动整合之间的相互作用。意义：空间注意可能调节感觉运动整合。 MEP 的传入抑制。 (c) 2004 年国际临床神经生理学联合会。由爱思唯尔爱尔兰有限公司出版。保留所有权利。
Objective: Recent transcranial magnetic stimulation (TMS) studies showed that the sensory input can decrease the motor cortex excitability (afferent inhibition). To clarify the effect of attention on sensorimotor integration, we investigated the effect of spatial attention on afferent inhibition.Methods: Right median nerve electrical stimulation followed, at variable delays (10-300 ms), by TMS over the left motor cortex was applied to 9 subjects, during 3 conditions; spatial attention to the right and left hand, and control (no attention) tasks.Results: Inhibition of the motor evoked potential occurred at inter-stimulus interval of 20 and 100 ms, which was more was marked during spatial attention to the right than to the left hand.Conclusions: Enhancement of the afferent inhibition induced by spatial attention to the stimulated side is likely to reflect the interaction between attention and sensorimotor integration.Significance: The spatial attention may modulate the sensorimotor integration studied by afferent inhibition of the MEP. (c) 2004 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.