2016 Focused Update: Clinical Recommendations for Cardiopulmonary Exercise Testing Data Assessment in Specific Patient Populations

2016 Focused Update: Clinical Recommendations for Cardiopulmonary Exercise Testing Data Assessment in Specific Patient Populations
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DOI:
10.1161/cir.0000000000000406
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发表时间:
2016-06-14
期刊:
影响因子:
37.8
通讯作者:
Lavie, Carl J.
Lavie, Carl J.
中科院分区:
医学1区
文献类型:
--
作者:
Guazzi, Marco;Arena, Ross;Lavie, Carl J.

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在过去的几十年里,心肺运动试验(CPX)的证据基础呈指数级增长。支持CPX的证据越来越多,促使社会和协会发布了许多科学声明。2012年,欧洲心血管预防与康复协会和美国心脏协会联合制定了一份文件,主要目的是重新定义CPX分析和报告,以简化测试解释并增加临床应用。具体而言,2012年关于CPX的联合科学声明基于颜色编码算法中的证据审查变量,概念化了一种易于使用、具有临床意义的分析;针对每种拟议的测试适应症成功开发了单页算法。由于近年来大量新的CPX研究以及根据大量证据对当前算法的重新评估,现在有必要对2012年的科学声明进行重点更新。本次更新的目的是确认初始科学声明中包含的无需修订的算法,对初始科学声明中包含的算法提出修订建议,根据新出现的科学证据提出新算法,进一步阐明阐明临界氧耗量的应用,用新出现的科学证据基础描述CPX变量,描述CPX与其他评估相结合的协同价值,讨论CPX实验室的人员考虑,并为未来的CPX研究提供建议。
In the past several decades, cardiopulmonary exercise testing (CPX) has seen an exponential increase in its evidence base. The growing volume of evidence in support of CPX has precipitated the release of numerous scientific statements by societies and associations. In 2012, the European Association for Cardiovascular Prevention & Rehabilitation and the American Heart Association developed a joint document with the primary intent of redefining CPX analysis and reporting in a way that would streamline test interpretation and increase clinical application. Specifically, the 2012 joint scientific statement on CPX conceptualized an easy-to-use, clinically meaningful analysis based on evidence-vetted variables in color-coded algorithms; single-page algorithms were successfully developed for each proposed test indication. Because of an abundance of new CPX research in recent years and a reassessment of the current algorithms in light of the body of evidence, a focused update to the 2012 scientific statement is now warranted. The purposes of this update are to confirm algorithms included in the initial scientific statement not requiring revision, to propose revisions to algorithms included in the initial scientific statement, to propose new algorithms based on emerging scientific evidence, to further clarify the application of oxygen consumption at ventilatory threshold, to describe CPX variables with an emerging scientific evidence base, to describe the synergistic value of combining CPX with other assessments, to discuss personnel considerations for CPX laboratories, and to provide recommendations for future CPX research.