PHILOSOPHY OF DISEASE ERADICATION
PHILOSOPHY OF DISEASE ERADICATION
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DOI：
10.2105/ajph.53.1.1
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发表时间：
1963-01-01
期刊：
影响因子：
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通讯作者：
LANGMUIR, AD
中科院分区：
文献类型：
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作者：
ANDREWS, JM;LANGMUIR, AD
通过无限乐观的技术时期出现的疾病根除概念，被病原体生存和转移的微妙机制的揭示所缓和。但考虑到巴西取得的辉煌成就，如从巴西地区根除黄热病蚊媒(1925年)和暴发性疟疾(1940年)，悲观是不合逻辑的。在美国，滴滴涕的使用使地方性斑疹伤寒病例从1944年的5400例减少到目前的约50例，疟疾作为地方性疾病已被根除。世界各国的努力(到1960年1月)从18个拥有1.08亿人口的国家或地区根除了疟疾。根除目标至少导致更高级别的控制，充其量导致目标生物的全球灭绝，这是预防医学的最高胜利。
Concept of disease eradication, emerging from superstitution through technologic period of boundless optimism, is tempered by revelations of subtle mechanisms of agent survival and transfer. But pessimism is illogical in view of brilliant achievements such as eradication from areas of Brazil of yellow fever mosquito vector (1925) and of fulminant malaria (1940). Use of DDT in U.S. reduced endemic typhus from 5400 cases in 1944 to about 50 currently, and malaria has been eradicated as an endemic disease. World efforts had eradicated malaria (by Jan. 1960) from 18 countries or territories with 108 million population. Eradication goal leads, at least, to higher order of control and, at best, to global extinction of target organism, the supreme victory of preventive medicine.