Human embryoid bodies containing nano- and microparticulate delivery vehicles

Human embryoid bodies containing nano- and microparticulate delivery vehicles
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DOI:
10.1002/adma.200702404
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发表时间:
2008-06-18
期刊:
影响因子:
29.4
通讯作者:
Langer, Robert
Langer, Robert
中科院分区:
材料科学1区
文献类型:
--
作者:
Ferreira, Lino;Squier, Trevor;Langer, Robert

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人胚胎干细胞的分化受胚状体中生长因子释放颗粒的掺入影响。这些颗粒的掺入对细胞活力和增殖的影响很小,但对分化的影响很大。图中显示了通过共聚焦显微镜评估的tritc标记微粒在胚状体中的分布。
Differentiation of human embryonic stem cells is affected by the incorporation of growth-factor-releasing particles in embryoid bodies. Incorporation of these particles has a minimal effect on cell viability and proliferation but a large impact on differentiation. The figure shows the distribution of TRITC-labeled microparticles in embryoid bodies, as evaluated by confocal microscopy.