Integrated multilayer flow system on a microchip
Integrated multilayer flow system on a microchip
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DOI：
10.2116/analsci.17.89
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发表时间：
2001-01-01
影响因子：
1.6
通讯作者：
Kitamori, T
中科院分区：
文献类型：
--
作者：
Hibara, A;Tokeshi, M;Kitamori, T
我们利用微芯片技术，发现液体的多层流动可以在微通道中形成。由于表面张力和摩擦力大于重力，液/液界面平行于微通道侧壁形成。水/乙酸乙酯/水界面在70 μ m宽和30 μ m深的通道中形成。观察到界面相当稳定，并保持超过18 cm的距离。作为多层流动应用的一个例子，我们展示了在微通道中的Co-二甲基氨基苯酚络合物的液/液萃取。发现在多层流中络合物到间二甲苯的溶剂萃取过程在4 s内达到平衡，而在简单的两相萃取中需要60 s。
We utilized microchip technology and found that the multilayer flow of liquids can be formed in microchannels. Liquid/liquid interfaces were formed parallel to the side wall of the microchannels, because the surface tension and friction force are stronger than the force of gravity. A water/ethylacetate/water interface was formed in a 70-mum-wide and 30-mum-deep channel. The interface was observed to be quite stable and to be maintained for a distance of more than 18 cm. As an example of a multilayer flow application, we demonstrated the liquid/liquid extraction of Co-dimethylaminophenol complex in a microchannel. The solvent-extraction process of the complex into m-xylene in the multilayer flow was found to reach equilibrium in 4 s, while it took 60 s in a simple two-phase extraction.