Parasite local adaptation in a geographic mosaic
Parasite local adaptation in a geographic mosaic
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DOI：
10.1111/j.0014-3820.2006.tb01078.x
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发表时间：
2006-01-01
期刊：
影响因子：
3.3
通讯作者：
Nuismer, SL
中科院分区：
文献类型：
--
作者：
Nuismer, SL
共同进化的地理镶嵌理论的一个核心预测是，共同进化的种间相互作用将表现出不同程度的局部适应不良。根据该理论，这种局部适应不良在很大程度上是由选择镶嵌和空间上混合的共同进化热点和冷点驱动的，而不是基因流动和选择之间的简单平衡。在这里，我开发了一个宿主-寄生虫共同进化的遗传模型，该模型具有足够的普遍性，可以将选择镶嵌，共同进化的热点和冷点以及各种各样的感染/抗性遗传系统结合起来。从这个模型的结果表明，相互作用的物种所经历的选择马赛克是一个重要的决定因素的迹象和规模的地方适应不良。在某些情况下，这种影响可能比先前描述的寄生虫和宿主基因流的相对速率的影响更强。这些结果提供了第一个理论证据，即选择马赛克和共同进化的热点和冷点本身决定了当地适应不良的程度和迹象。然而，与此同时，这些结果表明，地理镶嵌中的共同进化几乎可以导致任何局部适应或局部适应不良的模式。因此，仅描述局部适应或适应不良模式的实证研究并不能提供支持或反对该理论的证据。
A central prediction of the geographic mosaic theory of coevolution is that coevolving interspecific interactions will show varying degrees of local maladaptation. According to the theory, much of this local maladaptation is driven by selection mosaics and spatially intermingled coevolutionary hot and cold spots, rather than a simple balance between gene flow and selection. Here I develop a genetic model of host-parasite coevolution that is sufficiently general to incorporate selection mosaics, coevolutionary hot and cold spots, and a diverse array of genetic systems of infection/resistance. Results from this model show that the selection mosaics experienced by the interacting species are an important determinant of the sign and magnitude of local maladaptation. In some cases, this effect may be stronger than a previously described effect of relative rates of parasite and host gene flow. These results provide the first theoretical evidence that selection mosaics and coevolutionary hot and cold spots per se determine the magnitude and sign of local maladaptation. At the same time, however, these results demonstrate that coevolution in a geographic mosaic can lead to virtually any pattern of local adaptation or local maladaptation. Consequently, empirical studies that describe only patterns of local adaptation or maladaptation do not provide evidence either for or against the theory.