Nanomaterial-based electrochemical biosensors for medical applications
Nanomaterial-based electrochemical biosensors for medical applications
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DOI：
10.1016/j.trac.2008.05.004
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发表时间：
2008-07-01
影响因子：
13.1
通讯作者：
Tamiya, Eiichi
中科院分区：
文献类型：
--
作者：
Kerman, Kagan;Saito, Masato;Tamiya, Eiichi
随着近年来纳米技术的发展，基于纳米材料的生物传感器取得了很大的进展，但仍有许多挑战需要克服。我们为该领域的新研究人员描述了基于纳米材料的生物传感器，特别关注金属纳米颗粒和基于碳纳米管（CNT）的无标签方法。生物识别事件的无标签监测提供了一个很有前途的平台，它简单、经济、不需要对生物分子进行外部修饰。使用最近报告中的例子，我们说明了生物识别事件的多样性以及用于基于金属纳米颗粒和无标记表征的实验技术的范围。(C) 2008 Elsevier Ltd版权所有。
With recent advances in nanotechnology, great progress has been made in biosensors based on nanomaterials, but there are still numerous challenges to overcome. We describe nanomaterial-based biosensors for researchers new to the field, paying particular attention to metal nanoparticles and carbon nanotube (CNT)-based label-free approaches. Label-free monitoring of biorecognition events provides a promising platform, which is simple, cost-effective, and requires no external modification to biomolecules. Using examples from recent reports, we illustrate the diversity of biological recognition events and the range of experimental techniques employed for metal-nanoparticle-based and label-free characterization. (C) 2008 Elsevier Ltd. All rights reserved.