Hantavirus infection mimicking leptospirosis: how long are we going to rely on clinical suspicion?

Hantavirus infection mimicking leptospirosis: how long are we going to rely on clinical suspicion?
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DOI:
10.3855/jidc.4115
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发表时间:
2014-08-01
影响因子:
1.9
通讯作者:
Vinetz, Joshep M.
Vinetz, Joshep M.
中科院分区:
医学4区
文献类型:
--
作者:
Dahanayaka, Niroshana J.;Agampodi, Suneth B.;Vinetz, Joshep M.

文献摘要

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汉坦病毒感染和钩端螺旋体病可能具有相似的临床和流行病学特征。本文介绍了2011年斯里兰卡阿努拉德普勒省洪水后钩端螺旋体病暴发期间一位年轻农民发烧的案例研究。他表现出钩端螺旋体病的典型临床表现,并作为钩端螺旋体病病例进行处理和通报。对储存的血清样本进行回顾性分析,证实急性汉坦病毒感染。由于发展中国家缺乏诊断设施,对汉坦病毒感染等新发现或新出现的传染病的诊断具有挑战性。这一病例突出表明,有必要改善斯里兰卡的诊断设施,对医务人员进行教育,并开展以人群为基础的汉坦病毒感染前瞻性研究。
Hantavirus infections and leptospirosis can have similar clinical and epidemiological features. We present here a case study of a young farmer with fever during the post-flood leptospirosis outbreak in Anuradhapura, Sri Lanka, in 2011. He presented with a classical clinical picture of leptospirosis and was managed and notified as a case of leptospirosis. Retrospective analysis of a stored serum sample confirmed acute hantavirus infection. Diagnosis of newly identified or emerging infectious diseases such as hantavirus infection is challenging due to the lack of diagnostic facilities in developing countries. This case highlights the need for improving diagnostic facilities, educating medical staff, and conducting population-based prospective studies on hantavirus infections in Sri Lanka.