Impact of paraquat regulation on suicide in South Korea
Impact of paraquat regulation on suicide in South Korea
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DOI：
10.1093/ije/dyv304
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发表时间：
2016-04-01
影响因子：
7.7
通讯作者：
Lee, Won Jin
中科院分区：
文献类型：
--
作者：
Cha, Eun Shil;Chang, Shu-Sen;Lee, Won Jin
背景：2006年至2010年，摄入杀虫剂（主要是百草枯）占韩国自杀人数的五分之一。我们调查了监管行动对自杀死亡率的影响，最终在2011- 12年韩国禁止百草枯。方法：我们使用登记的死亡数据计算了韩国（1983-2013年）年龄为千分之一日元15的人群的年龄标准化方法特异性自杀死亡率。采用负二项回归估计2013年农药自杀率和数量的变化，与基于先前趋势（2003-11）的预期相比。结果：2011年至2013年，农药自杀死亡率从每10万人口5.26人减半至2.67人。与基于先前趋势的预期数量相比，2013年，该法规实施后估计减少了847例[95%置信区间（CI）-1180至533]农药自杀，比率下降了37%（比率= 0.63，95% CI 0.55至0.73）。管制后，所有年龄/性别/地理群体的农药自杀率都有所下降。男子、老年人和农村地区自杀人数的绝对下降幅度最大。2011年至2013年，农药自杀的减少占自杀总数下降的56%。有没有影响的规定对作物yield.Conclusions：在韩国的百草枯在2011-12年的监管与减少农药自杀。建议采取进一步的立法干预措施，防止高致命性自杀方法的轻易获得，以减少世界各地的自杀人数。
Background: Ingestion of pesticides (mainly paraquat) accounted for one-fifth of suicides in South Korea in 2006-10. We investigated the effect on suicide mortality of regulatory action, culminating in a ban on paraquat in South Korea in 2011-12.Methods: We calculated age-standardized method-specific suicide mortality rates among people aged a parts per thousand yen15 in South Korea (1983-2013) using registered death data. Negative binomial regression was used to estimate changes in the rate and number of pesticide suicides in 2013, compared with those expected based on previous trends (2003-11).Results: Pesticide suicide mortality halved from 5.26 to 2.67 per 100 000 population between 2011 and 2013. Compared with the number expected based on previous trends, the regulations were followed by an estimated 847 [95% confidence interval (CI) -1180 to -533] fewer pesticide suicides, a 37% reduction in rates (rate ratio = 0.63, 95% CI 0.55 to 0.73) in 2013. The decline in pesticide suicides after the regulations was seen in all age/sex/geographical groups. The absolute reduction in the number of suicides was greatest among men, the elderly and in rural areas. The reduction in pesticide suicides contributed to 56% of the decline in overall suicides that occurred between 2011 and 2013. There was no impact of the regulations on crop yield.Conclusions: The regulation of paraquat in South Korea in 2011-12 was associated with a reduction in pesticide suicide. Further legislative interventions to prevent the easy availability of highly lethal suicide methods are recommended for reducing the number of suicides worldwide.