Synthesis and Characterization of Silicon-Doped Hydroxyapatite
Synthesis and Characterization of Silicon-Doped Hydroxyapatite
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DOI：
10.2320/matertrans.mc200808
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发表时间：
2009-05-01
影响因子：
1.2
通讯作者：
Nakahira, Atsushi
中科院分区：
文献类型：
--
作者：
Nakata, Kentaro;Kubo, Takashi;Nakahira, Atsushi
通过水热技术将硅掺杂到羟基磷灰石中以获得更高的生物相容性。产品含有0至15质量％的原硅酸四乙酯(TEOS)作为硅源。为了评估硅掺杂羟基磷灰石的生物活性，将样品浸泡在模拟体液（SBF）中。硅掺杂样品显示出比未掺杂样品更快的磷灰石形成能力。通过透射电子显微镜（TEM）、X射线衍射图谱（XRD）、傅里叶变换红外光谱（FTIR）和X射线吸收精细结构（XAFS）对样品进行了检查。结果表明，磷灰石结构中SiO44-离子取代了PO43-离子位点。结果发现，由于 15 质量％ TEOS 掺杂样品中存在非晶态 SiO2 偏析，因此合适的 TEOS 掺杂比例为 10 质量％，具有优异的生物相容性。 [doi:10.2320/matertrans.MC200808]
Silicon was doped to hydroxyapatite by hydrothermal techniques for higher biocompatibility. Products contained tetra-ethyl-orthosilicate (TEOS) as a silicon source in the range of 0 to 15 mass%. In order to evaluate bioactivity of silicon-doped hydroxyapatite, the samples were soaked in Simulated body fluid (SBF). Silicon doped samples showed faster apatite forming ability than the undoped samples. The samples were examined by transmission electron microscopy (TEM), X-ray diffraction patterns (XRD), Fourier transform infrared spectroscopy (FTIR) and X-ray absorption fine structure (XAFS). There results indicated that SiO44- ion substituted PO43- ion site in apatite structures. And it was found that appropriate TEOS doping ratio was 10 mass% for superior biocompatibility due to amorphous SiO2 segregation in the 15 mass% TEOS doped samples. [doi:10.2320/matertrans.MC200808]