Directional Bias in Line Orientation Test Errors in Parkinson's Disease.
Directional Bias in Line Orientation Test Errors in Parkinson's Disease.
复制标题
帕金森病的线方向测试错误中的方向偏差。
DOI：
10.1093/arclin/acaa020
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发表时间：
2020
期刊：
影响因子：
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通讯作者：
Wilson,Randi
中科院分区：
文献类型：
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作者：
Riordan,Patrick;Kletzel,SandraL;Lahr,Genessa;Walter,Jamie;Wilson,Randi
目的评价视觉空间线定向测试中误差亚型的价值。线定向测试误差的方向偏差度量表示以前没有研究过的容易量化的数据。我们评估了具有已知影响视空间功能的临床疾病(帕金森病[PD])的患者在RBANS线条定向测试中是否表现出相对于其他神经心理学参考患者的独特的方向错误模式。方法我们比较了回顾的PD患者样本和神经心理学参考的非PD患者样本中错误的总体方向偏向、线条位置(左侧或右侧线条和视野)的方向偏向以及线条位置的绝对错误率(无论方向)。两组在年龄、教育程度、性别和总体认知障碍水平上大致匹配。结果帕金森病患者在错误中表现出更高的左倾率，无论是总体上还是在每对患者的左侧刺激线上都是如此。方向偏差误差分数比RBANS直线定位原始分数更好地预测PD与非PD组的状态。这些变量的分类精度数据在整个样本中并不高，但在总体认知障碍程度较轻的患者的子样本中更强。结论直线定向测试的方向偏差度量代表了易于量化的数据，具有潜在的理论和临床价值。在我们的样本中，帕金森病患者比其他神经心理学转诊患者犯了更多的左倾线方向错误。方向性偏向评分本身可能具有有限的诊断潜力，但它们在诊断分类模型中可能有用，并可能对临床护理产生影响。
ObjectiveValue in evaluating error subtypes on visuospatial line orientation tests has been reported. Directional bias metrics for line orientation test errors represent easily quantifiable data that have not previously been studied. We evaluated whether patients with a clinical condition known to affect visuospatial functioning (Parkinson’s disease [PD]) exhibited unique directional error patterns on the RBANS Line Orientation test relative to other neuropsychology-referred patients.MethodWe compared overall directional bias in errors, directional bias by line location (left or right line and visual field), and absolute error rates (regardless of direction) by line location in a retrospective sample of patients with PD and a sample of neuropsychology-referred patients without PD. Groups were roughly matched on age, education, gender, and overall level of cognitive impairment.ResultsPatients with PD exhibited higher rates of leftward bias in errors, both overall and for the left stimulus line in each pair. Directional bias error scores better predicted PD versus non-PD group status than RBANS Line Orientation raw scores. Classification accuracy data for these variables were modest in the entire sample but stronger in a subsample of patients with mild levels of overall cognitive impairment.ConclusionsDirectional bias metrics for line orientation tests represent easily quantifiable data with potential theoretical and clinical value. In our sample, patients with PD made more left-biased line orientation errors than other neuropsychology-referred patients. By themselves, directional bias scores may have limited diagnostic potential, but they may be useful in diagnostic classification models and may have implications for clinical care.