MACROMOLECULAR ABSORPTION IN PRETERM AND TERM INFANTS
MACROMOLECULAR ABSORPTION IN PRETERM AND TERM INFANTS
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DOI：
10.1111/j.1651-2227.1989.tb17932.x
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发表时间：
1989-07-01
期刊：
影响因子：
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通讯作者：
RAIHA, N
中科院分区：
文献类型：
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作者：
AXELSSON, I;JAKOBSSON, I;RAIHA, N
人α-乳清蛋白(α-LA)已被用作测量大分子吸收的标记物。已经在32名健康极低出生体重婴儿(VLBW)、喂养母乳(孕龄26-32周)和56名足月、母乳喂养、年龄3-140天的婴儿中研究了母乳喂养后人α-LA的血清浓度。在妊娠31周时，人α-LA的血清浓度比3-30天的足月婴儿(平均值257和中值152，n=29)高10倍以上(平均值3000和中值2101μg/l血清/l母乳/kg体重，n=11)。在VLBW婴儿中，α-LA的血清浓度随着成熟度的增加而降低。受孕后 37 周时的数值与足月婴儿第一个月的数值相似（平均值 200，中位值 99，n = 8）。在足月婴儿中，发现随着出生后年龄的增加，α-LA的吸收减少。
Human .alpha.-lactalbumin (.alpha.-LA) has been used as a marker for measuring macromolecular absorption. The serum concentration of human .alpha.-LA after a human milk feed has been studied in 32 healthy very low-birthweight infants (VLBW), fed human milk (gestational age 26-32 weeks) and in 56 term, breast-fed infants, age 3-140 days. At 31 weeks of gestation the serum concentration of human .alpha.-LA was more then 10 times higher (mean value 3000 and median value 2101 .mu.g/l serum/l human milk/kg body weight, n=11) than in the term infants aged 3-30 days (mean value 257 and median value 152, n=29). The serum concentration of .alpha.-LA decreased with increasing maturity in the VLBW-infants. At a postconceptional age of 37 weeks the values were similar (mean value 200 and median value 99, n = 8) to those found for term infants during the first month. In the term infants a decreasing absorption of .alpha.-LA was found with increasing postnatal age.