Safety and efficacy of spinal cord stimulation for the treatment of chronic pain: a 20-year literature review
Safety and efficacy of spinal cord stimulation for the treatment of chronic pain: a 20-year literature review
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DOI：
10.3171/spi.2004.100.3.0254
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发表时间：
2004-03-01
影响因子：
4.1
通讯作者：
Cameron, T
中科院分区：
文献类型：
--
作者：
Cameron, T
对象。本报告的目的是检查现有的文献，以确定脊髓刺激（SCS）治疗躯干和四肢慢性疼痛的安全性和有效性。作者确定了68项符合疗效纳入/排除标准的研究，根据疼痛指征进行分组，总共有3679名患者。51项研究符合所有安全纳入/排除标准。通过文献综述，作者发现SCS对难治性心绞痛、继发于周围血管疾病的严重缺血性肢体疼痛、周围神经性疼痛和慢性腰痛具有阳性、对症、长期的疗效，总的来说，SCS是一种安全有效的治疗多种慢性神经性疾病的方法。尽管有这些积极的发现，但迫切需要对SCS的疗效进行随机、对照、长期的研究，涉及更大的患者样本量。
Object. The purpose of this report was to examine the available literature to determine the safety and efficacy of spinal cord stimulation (SCS) for the treatment of chronic pain of the trunk and limbs.Methods. The author identified 68 studies that fulfilled the efficacy inclusion/exclusion criteria, grouped on the basis of pain indication, with an overall population of 3679 patients. Fifty-one studies fulfilled all safety inclusion/exclusion criteria. Based on the literature review, the author found that SCS had a positive, symptomatic, long-term effect in cases of refractory angina pain, severe ischemic limb pain secondary to peripheral vascular disease, peripheral neuropathic pain, and chronic low-back pain, and that, in general, SCS was a safe and effective treatment for a variety of chronic neuropathic conditions.Conclusions. Despite the positive findings, there is an urgent need for randomized, controlled, long-term studies on the efficacy of SCS involving larger patient sample sizes.