Optic neuritis in pediatric population: a review in current tendencies of diagnosis and management.
Optic neuritis in pediatric population: a review in current tendencies of diagnosis and management.
复制标题
DOI：
10.1016/j.optom.2013.12.008
复制
发表时间：
2014-07-01
影响因子：
2.3
通讯作者：
Laria-Ochaita, Carlos
中科院分区：
文献类型：
--
作者：
Perez-Cambrodi, Rafael Jose;Gomez-Hurtado Cubillana, Aranzazu;Laria-Ochaita, Carlos
视神经炎是视神经的炎症，可能与不同的全身状况有关。这种病理学的临床表现通常包括单侧或双侧视力突然丧失、视野受限、眼球运动疼痛、色盲、相对传入瞳孔缺陷和视盘肿胀。儿童视神经炎具有特定的临床特征，且预后优于成人。尽管通常表现为潜在的病毒性疾病，但从业者主要关心的是视神经炎与多发性硬化症的关系。除了磁共振成像 (MRI) 等经典技术之外，目前眼科医师的诊断趋势还包括光学相干断层扫描 (OCT) 等新型成像设备，可用于显示炎症发作后视网膜纤维层 (RFL) 的变薄情况。关于这些患者的治疗，短期静脉注射类固醇剂量似乎是治疗以双侧视力极差为特征的急性发作的最佳选择。
Optic neuritis is an inflammation of the optic nerve and may be related to different systemic conditions. The clinical presentation of this pathology usually includes sudden loss of visual acuity (VA) which may be unilateral or bilateral, visual field restriction, pain with eye movements, dyschromatopsia, a relative afferent pupillary defect and optic disk swelling. Optic neuritis in children has specific clinical features and a better prognosis than in adulthood. Although usually appears an underlying viral disease, the main concern for practitioners is the relationship of optic neuritis with multiple sclerosis. In addition to the classical techniques as magnetic resonance imaging (MRI), current tendencies of diagnosis for eye practitioners include new imaging devices as optical coherence tomography (OCT), useful to show a thinning of the retinal fibers layer (RFL) after the inflammatory episode. Regarding the management of these patients, short-term intravenous steroid dosages seem to be the best option to treat acute attacks characterized by a very poor bilateral VA.