Phosphatase/temperature responsive poly(2-isopropyl-2-oxazoline)

Phosphatase/temperature responsive poly(2-isopropyl-2-oxazoline)
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DOI:
10.1039/c0py00291g
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发表时间:
2011-01-01
期刊:
影响因子:
4.6
通讯作者:
Ulijn, Rein V.
Ulijn, Rein V.
中科院分区:
化学2区
文献类型:
--
作者:
Caponi, Pier-Francesco;Qiu, Xing-Ping;Ulijn, Rein V.

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We demonstrate a strategy for producing polymer bioconjugates which display both enzymatic and thermal responsiveness. This is achieved by combining the thermo-responsive properties of poly(2-isopropyl-2-oxazoline) (PiPrOx) with the self-assembly properties of fluorenylmethoxycarbonyl-tyrosine (Fmoc-Y), controlled by a phosphatase triggered mechanism.