Tomato juice intake increases resting energy expenditure and improves hypertriglyceridemia in middle-aged women: an open-label, single-arm study
Tomato juice intake increases resting energy expenditure and improves hypertriglyceridemia in middle-aged women: an open-label, single-arm study
复制标题
番茄汁摄入会增加中年女性的静息能量消耗并改善高甘油三酯血症：一项开放标签、单臂研究
DOI：
--
复制
发表时间：
2015
期刊：
影响因子：
--
通讯作者：
T. Kubota
中科院分区：
文献类型：
--
作者：
A. Hirose;M. Terauchi;Moe Tamura;M. Akiyoshi;Y. Owa;K. Kato;T. Kubota
研究背景番茄食品具有促进健康和预防疾病的作用。一些番茄汁成分可能对中年妇女有健康益处，包括有更年期症状和心血管疾病的妇女。我们调查了净效应的番茄汁摄入量在这个年龄组的妇女在几个健康参数。MethodsAn开放标签，单臂研究进行，涉及95名妇女（40-60岁）谁至少有一个更年期症状。参与者在研究前2周和8周的番茄汁消费期间避免富含番茄和番茄制品的食物和饮料。在磨合期后，这些女性被要求每天两次饮用200毫升无盐番茄汁，持续8周。在研究开始前、研究开始后4周和8周，使用月经症状量表（MSS）、医院焦虑和抑郁量表（HADS）和雅典抑郁量表（AIS）评估她们的绝经症状。在同一时间，身体成分;血压;心率;静息能量消耗（REEs）;和血清水平的甘油三酯（TG），胆固醇，葡萄糖，血红蛋白A1 C进行了measured. ResultsNine-3名妇女（98%）完成了研究。在研究第4周和第8周，与基线相比，以下参数显示出显著变化（基线、第4周和第8周的平均值±标准差）：（1）MSS评分改善（9.9 ± 5.2，8.5 ± 5.0，8.3 ± 5.0; P < 0.0001，重复测量方差分析（ANOVA））。（2）HADS-焦虑子量表得分提高（5.3 ± 2.7，4.8 ± 2.4，4.9 ± 2.9; P = 0.041，Friedman检验），（3）心率增快（62.6 ± 9.4 bpm，64.4 ± 8.6 bpm，63.8 ± 8.2 bpm; P = 0.028，Friedman检验）;（4）REE升高（1980 ± 368千卡/天，2108 ± 440千卡/天，2149 ± 470千卡/天; P = 0.0030，重复测量方差分析），（5）高TG妇女亚组（n = 22）血清TG水平降低基线时（≥ 150 mg/dL）（237.8 ± 88.9 mg/dL，166.7 ± 86.1 mg/dL，170.9 ± 109.7 mg/dL; P = 0.0002，Friedman检验）。结论番茄汁摄入量减轻更年期症状，包括焦虑，增加稀土和心率，并降低中年妇女的高基线血清TG水平。
BackgroundTomato-based food products have health-promoting and disease-preventing effects. Some tomato juice ingredients may have health benefits for middle-aged women, including women with menopausal symptoms and cardiovascular diseases. We investigated the net effect of tomato juice intake on several health parameters in women in this age group.MethodsAn open-label, single-arm study was conducted, involving 95 women (40-60-years-old) who had at least one menopausal symptom. The participants refrained from foods and drinks rich in tomato and tomato-based products for 2 weeks prior to the study and during the 8 weeks of tomato juice consumption. After the run-in period, the women were asked to consume 200 mL of unsalted tomato juice, twice daily for 8 weeks. Their menopausal symptoms were evaluated using the Menopausal Symptom Scale (MSS), Hospital Anxiety and Depression Scale (HADS), and Athens Insomnia Scale (AIS) before the study, and at 4 and 8 weeks after study commencement. At the same times, body composition; blood pressure; heart rate; resting energy expenditures (REEs); and serum levels of triglyceride (TG), cholesterol, glucose, and hemoglobin A1c were measured.ResultsNinety-three women (98%) completed the study. The following parameters showed significant changes, compared with baseline, at study weeks 4 and 8 (mean ± standard deviation at baseline, week 4, and week 8): (1) the MSS score improved (9.9 ± 5.2, 8.5 ± 5.0, 8.3 ± 5.0; P < 0.0001, repeated measures analysis of variance(ANOVA)), (2) the HADS-anxiety subscale score improved (5.3 ± 2.7, 4.8 ± 2.4, 4.9 ± 2.9; P = 0.041, Friedman test), (3) heart rate increased (62.6 ± 9.4 bpm, 64.4 ± 8.6 bpm, 63.8 ± 8.2 bpm; P = 0.028, Friedman test), (4) REE increased (1980 ± 368 kcal/day, 2108 ± 440 kcal/day, 2149 ± 470 kcal/day; P = 0.0030, repeated measures ANOVA), (5) serum TG level decreased in the subgroup of women (n = 22) who had high TG (150 mg/dL or higher) at baseline (237.8 ± 88.9 mg/dL, 166.7 ± 86.1 mg/dL, 170.9 ± 109.7 mg/dL; P = 0.0002, Friedman test).ConclusionsTomato juice intake alleviated menopausal symptoms, including anxiety, increased REEs and heart rate, and lowered high baseline serum TG levels in middle-aged women.Trial registrationUMIN-CTRUMIN000011877.
DOI：
--
发表时间：
2012
期刊：
--
影响因子：
--
作者：
A. Gabor;F. Leenen
通讯作者：
A. Gabor;F. Leenen
影响因子：
4.2
作者：
Sesso, HD;Liu, SM;Buring, JE
通讯作者：
Buring, JE
影响因子：
12.4
作者：
Story EN;Kopec RE;Schwartz SJ;Harris GK
通讯作者：
Harris GK