Changes in Hospital Mortality Rates in 425 Patients With Acute ST-Elevation Myocardial Infarction and Cardiac Rupture Over a 30-Year Period
Changes in Hospital Mortality Rates in 425 Patients With Acute ST-Elevation Myocardial Infarction and Cardiac Rupture Over a 30-Year Period
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DOI：
10.1161/circulationaha.108.776690
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发表时间：
2008-12-16
期刊：
影响因子：
37.8
通讯作者：
Lidon, Rosa-Maria
中科院分区：
文献类型：
--
作者：
Figueras, Jaume;Alcalde, Oscar;Lidon, Rosa-Maria
背景--ST段抬高心肌梗死患者心脏破裂的发生率和结局的可能变化尚未被研究。方法和结果：将ST段抬高心肌梗死患者分为5个时段(1977-1982、1983-1988、1989-1994、1995-2000和2001-2006年)，调查了30年间心脏破裂的发生率和死亡率。在总共6678名连续患者中，425名患者经历了游离壁破裂(280例合并心脏压塞：227例合并机电分离，53例合并低血压)或间隔破裂(145例)。排除其他中心的转诊后(n=44)，明确的心脏破裂(间隔破裂、游离壁破裂的解剖学证据或机电分离)的发生率逐渐下降(1977~1982年为6.2%，2001~2006年为3.2%；P
Background-Possible changes in the incidence and outcome of cardiac rupture in patients with ST-elevation myocardial infarction over a long period of time have not been investigated.Methods and Results-The incidence of cardiac rupture in ST-elevation myocardial infarction patients and its mortality rate were investigated during a 30-year period divided into 5 intervals (1977 to 1982, 1983 to 1988, 1989 to 1994, 1995 to 2000, and 2001 to 2006). Of a total of 6678 consecutive patients, 425 experienced a free wall rupture (280 with cardiac tamponade: 227 with electromechanical dissociation and 53 with hypotension) or a septal rupture (145). After the exclusion of referrals from other centers (n=44), the incidence of definite cardiac rupture (septal rupture, anatomic evidence of free wall rupture, or electromechanical dissociation) declined progressively (6.2% in 1977 to 1982 to 3.2% in 2001 to 2006; P