Palladium-Catalyzed Dehydrogenation Coupling–Cyclization Reactions of Acetylenic Acids with Iodonium Ylides for the Synthesis of 2(5H)-Furanones
Palladium-Catalyzed Dehydrogenation Coupling–Cyclization Reactions of Acetylenic Acids with Iodonium Ylides for the Synthesis of 2(5H)-Furanones
复制标题
钯催化脱氢偶联 — 乙炔酸与碘叶立德的环化反应用于合成 2(5H)-呋喃酮
DOI：
10.1055/s-0035-1560554
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发表时间：
2015-12
期刊：
影响因子：
2
通讯作者：
Han-Zhou Sun
中科院分区：
文献类型：
--
作者：
Bo Ca;Hong-Bo Xiao;Shao-Feng Pi*;Han-Zhou Sun
摘要以碳酸钾为碱，Pd（PPh 3）4为催化剂，催化炔酸与碘鎓叶立德的级联反应，合成了2（5 H）-呋喃酮。该级联反应在温和条件下通过脱氢、偶联和环合进行。
Abstract A new route for the synthesis of 2(5H)-furanones is presented via Pd(PPh3)4-catalyzed cascade reaction of acetlenic acids with iodonium ylides using K2CO3 as the base. The cascade proceeds through dehydrogenation coupling and cyclization under mild conditions.