Electron Microscopic Investigation of Sulcus Vocalis
Electron Microscopic Investigation of Sulcus Vocalis
复制标题
声沟的电子显微镜检查
DOI：
10.1177/000348949810700111
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
M. Hirano
中科院分区：
文献类型：
--
作者：
Kiminori Sato;M. Hirano
本研究旨在探讨两例成人声带沟的组织病理学表现。通过光学和透射电子显微镜进行观察。结果总结如下。沟局限于鳞状上皮区域。基底膜厚度在沟处增加。沟位于固有层的浅层，在沟的底部周围是薄的。胶原纤维致密，在沟底部周围可见纤维状长间距胶原。弹性纤维数量减少，主要由微纤丝和网状无定形物质组成。黄斑区成纤维细胞数量减少，变性。黄斑成纤维细胞合成的胶原纤维和弹性纤维减少。黄斑内有许多异常弹性纤维。声带沟粘膜纤维成分的质量和数量发生了变化，部分原因是成纤维细胞功能障碍和黄斑异常纤维形成。
This investigation was carried out to determine the histopathologic findings of sulcus vocalis in two human adult larynges. Observations were made by light and transmission electron microscopy. The results are summarized as follows. Sulcus was confined to the squamous epithelium area. The basement membrane thickness increased at the sulcus. The sulcus was situated in the superficial layer of the lamina propria, which was thin around the bottom of the sulcus. Collagenous fibers were dense, and fibrous long-spacing collagen was seen around the bottom of the sulcus. Elastic fibers decreased in number and were composed predominantly of microfibrils and reticular amorphous substances. In the maculae flavae, the fibroblasts were decreased in number and degenerated. Collagenous and elastic fibers, synthesized by fibroblasts in the maculae flavae, were decreased. There were many abnormal elastic fibers in the maculae flavae. The quality and quantity of the fibrous components were changed in the mucosa of sulcus vocalis, owing in part to dysfunction of the fibroblasts and abnormal fibrogenesis in the maculae flavae.